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Yellow Fever

Yellow Fever. Allison Gregg. General History. thousands of years old originated in Africa brought to the U.S. in the 1500s. General History. Walter Reed discovered how YF is transmitted-mosquitoes Yellow Fever from yellow color from liver failure. General History and Structure.

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Yellow Fever

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  1. Yellow Fever Allison Gregg

  2. General History • thousands of years old • originated in Africa • brought to the U.S. in the 1500s

  3. General History • Walter Reed discovered how YF is transmitted-mosquitoes • Yellow Fever from yellow color from liver failure

  4. General History and Structure • Asian countries are habitats for mosquitoes that carry Yellow fever • Single stranded RNA • Shape: spheroidal

  5. How YF is Transmitted • 2 transmission methods: • “jungle cycle” • “urban cycle”

  6. How YF is Transmitted • can only be transmitted through mosquito bites • cannot survive outside its vector-the mosquito

  7. How YF is Transmitted • originally from monkeys • becomes permanently fixed in salivary glands of mosquito

  8. Who is affected

  9. Who is affected • tropical regions of Africa and South America • 30,000 deaths each year worldwide • estimate of 200,000 cases a year

  10. Who is affected • epidemics usually affect 20% of the population • unvaccinated populations can have death rates above 50%

  11. Symptoms • incubation period of 3-6 days • “acute” phase • “toxic” phase

  12. Symptoms • 15% go into “toxic phase” • 50% of “toxic” cause death • hard to diagnose disease

  13. Vaccine • a live-virus vaccine • Vaccine must be given every 10 years • 95% immunity a week after vaccination

  14. http://www.cdc.gov/ncidod/dvbid/yellowfever/ • http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002341/ • http://www.who.int/mediacentre/factsheets/fs100/en/ • http://www.yellowfever.com.au/vaccine.html • http://www.microscopy-uk.org.uk/mag/indexmag.html?http://www.microscopy-uk.org.uk/mag/art98/aedrol.html

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