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Project Update 10/9/08 Kevin Egan

Project Update 10/9/08 Kevin Egan. Hypothesis: Circulating Osteogenic Progenitor Cells are present in lesions of NHHO Goal: Test new Collagen type 1 antibody in human bone marrow tissue sample

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Project Update 10/9/08 Kevin Egan

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  1. Project Update 10/9/08Kevin Egan • Hypothesis: Circulating Osteogenic Progenitor Cells are present in lesions of NHHO • Goal: Test new Collagen type 1 antibody in human bone marrow tissue sample • Rational: Type 1 collagen is present in all bone and around blood vessels. Should be detectable in control bone sample.

  2. Type 1 collagen in bone marrow 40 X

  3. Type 1 collagen in bone marrow 200 X

  4. Type 1 collagen in bone marrow 400 X

  5. Type 1 collagen in bone marrow 400 X

  6. Type 1 collagen in bone marrow “Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix” Arthritis Res. 2002; 4(1): 30–35

  7. Type 1 collagen in bone marrow Abcam Antibody

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