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NEWGEN: Customized Bone Implants Initiative

NEWGEN COST Action fostering collaboration between academia, R&D centers, medical units, and companies for advanced biomaterials and implants in bone engineering. Includes workshops, training schools, STSM grants, and international mobility.

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NEWGEN: Customized Bone Implants Initiative

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  1. COST Action – MP1301 NEWGEN NEWGEN NEW GENERATION BIOMIMETIC AND CUSTOMIZED IMPLANTS FOR BONE ENGINEERING Dr. Francis Cambier Vienna (AT), August 28th - 29th, 2017

  2. Scientific context and objectives • Background / Problem statement: • Ageing population • Increasing expectations regarding quality of life • Increasing demand for procedures such as total hip replacements, bone reconstructions, spinal fusions… • New advances in biomaterials (improved processing, bioactivity and/or tailored shapes, enough structural integrity and bone integration/regeneration): currently under development at the laboratory scale • However: gap between academic R&D and commercial production, and between materials scientists and clinicians, • NEWGEN MoU objectives: This COST Action, NEWGEN, aims at creating the seed for the European research and industry collaboration, combining basic knowledge from academic laboratories, R&D centres, medical units from hospitals, and a significant number of companies, in the field of biomaterials to realize new functionalized, bioresorbable and customized bone substitutes and more reliable implants

  3. Chair: Dr. F. Cambier (BCRC, BE) Vice-Chair: Dr. P. Palmero (Politecnico di Torino, IT) www.cost-newgen.org Multi Partners  Unique opportunity to link European researchers to industries and end-users Training School – PATRAS (Greece) – May 10th, 2017

  4. Design and Synthesis of New Materials Manufacturing and Characterization of 3D-porous Scaffolds Functionalization of implants for improved functional and therapeutic effects In Vitro Evaluation of the Performance • 8 workshops • 7 calls for STSM (46 grantees up to now) • 2 training schools • More than 30 scientific publications Training School – PATRAS (Greece) – May 10th, 2017

  5. First job : learning COST rules… • ECI (ESR), SO, AO, GHM, STSM, CSO, CG, MC, … • Inclusivenesstargetedpolicy countries • Gender balance… • VADEMECUM!!!! (with a new version everyyear…) • E-COST system with

  6. Our consortium! Inclusiveness targeted policy countries in NEWGEN

  7. Our consortium! From 66 groups in the proposals in 2013, up to 167 groups at the end of the Action! 21 European countries signed the MoU before the start of the Action Up to now, 33 countries (on 36) joined NEWGEN Inclusiveness targeted policy countries in NEWGEN

  8. Overview of the consortium- status of the Action • Start of NEWGEN : October 2nd, 2013 / End : October 1st, 2017 • 33 countries + 3 IPC : USA + Canada + Australia • Whole consortium • 167 institutions • Universities: 89 • R&D Centers: 24 • Industry: 22 • Medicine: 22 • 327 contacts in the mailing list • Gender balance = 39% / Inclusiveness = 33%

  9. Overview of the consortium- status of the Action • Start of NEWGEN : October 2nd, 2013 / End : October 1st, 2017 • 33 countries + 3 IPC : USA + Canada + Australia • Whole consortium • 167 institutions • Universities: 89 • R&D Centers: 24 • Industry: 22 • Medicine: 22 • 327 contacts in the mailing list • Gender balance = 39% / Inclusiveness = 33%

  10. NEWGEN : 4 Years of a large European networking on biomaterials Withorganization of : Training Schools Workshops STSM Management Comittee and Core Group meetings

  11. 1st Training School in Madrid • June 17th to 19th, 2015 • 15 lectures • 60 students

  12. 2nd Training School in Patras • 12 lectures • 35 students • Poster contest • Bone structure and properties • Cell biology, Bone physiology; • Biocompatibility; Biointerphase; • Processing of materials and final surface characteristics; • Scaffold design, processing, biodegradation/resorption; • Mechanobiology; • Bone Tissue Engineering; • In vivo experimental procedures and Surgical aspects

  13. STSM: review

  14. STSM: review • 46 Grantees (mostly PhD and ECI), with a STSM mean duration of 40 days • 84 670€ dedicated to STSM, on the 600k€ of the total budget of the Action! (15%) • High quality of reports, and leading to scientific publications (13 + 6 in preparation) and oral presentations in international conferences (11 + 8 planned) • A very good tool to promote mobility of young researchers

  15. Workshops and meetings

  16. Workshops and meetings

  17. Workshops and meetings • 8 workshops with invited speakers, oral presentations, poster sessions, etc. • Torino (IT) • Nantes (FR) • La Valette (MT) • Sofia (BG) • Aveiro (PT) • Zlin (CZ) • Cluj-Napoca (RO) • Vienna (AT) • 5 Management Committees (Brussels, Torino, La Valette, Aveiro, Cluj-Napoca) and 6 Core Group meetings (Porto, Limerick, Riga, Stuttgart, Gothenburg, Zagreb)

  18. Specialthanks to all Local Organizers (1/2): • Paola Palmero (MC meeting + Workshop Torino, IT) • Fernando Monteiro (CG meeting Porto, PT) • Pierre Weiss (Workshop Nantes, FR) • Stuart Hampshire (CG meeting Limerick, IE) • Josette « Barbara » Camilleri (MC meeting + workshop La Valetta, MT) • Carmen Baudin (1st Summer School Madrid, ES) • Albena Daskalova (Workshop Sofia, BG) • Janis Locs (CG meeting Riga, LV)

  19. Special thanks to all Local Organizers (2/2): • Margarida Almeida (MC meeting + Workshop Aveiro, PT) • Norbert Schneider (CG meeting Stuttgart, DE) • Nabanita Saha (Workshop in Zlin, CZ) • Gabriel Furtos (MC meeting + Workshop Cluj-Napoca, RO) • Erik Adolfsson (CG meeting Gothenburg, SE) • Yannis Missirlis (2nd Summer School Patras, EL) • Stefan Scheiner (Final Event Vienna, AT) • Andreja Gajovic (CG meeting Zagreb, HR)

  20. Specialthanks to WG (+ vice) Leaders and coordinators • Paola Palmero Vice-Chair • Carmen Baudin / Anne Leriche WG1 • Jérôme Chevalier / Hilda Mulvihill WG2 • Erik Adolfsson / Norbert Schneider WG3 • Fernando Monteiro / Benjamin F. Gutierrez WG4 • Anne Leriche Website Coordinator • Eamonn De Barra Dissemination Coordinator • Stephane Hocquet STSM Coordinator • Véronique Huart Grant Holder Manager

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