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* Luis Zegarra Montes Prof. Dr . Mg. Med . - UPCH

H. H. C. TRASPLANTE RENAL ANTICIPADO. * Luis Zegarra Montes Prof. Dr . Mg. Med . - UPCH Jefe de la Unidad de Trasplante Renal. HNCH-MINSA. TRASPLANTE RENAL ANTICIPADO. TRASPLANTE RENAL ANTICIPADO. * Prevalencia: * Comunidad Europea: Población: Adulta (5%) Infantil (20%)

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* Luis Zegarra Montes Prof. Dr . Mg. Med . - UPCH

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  1. H H C TRASPLANTE RENAL ANTICIPADO * Luis Zegarra Montes Prof. Dr. Mg.Med. - UPCH Jefe de la Unidad de Trasplante Renal. HNCH-MINSA.

  2. TRASPLANTE RENALANTICIPADO

  3. TRASPLANTE RENALANTICIPADO * Prevalencia: * Comunidad Europea: Población: Adulta (5%) Infantil (20%) Suecia: 70% (niños). Noruega: 15% (adultos). España: 2-3% (adultos) y 50% (niños). * Registro americanos: 20-25%. * Morales Ruiz E.: Trasplante Renal Anticipado. Guía SEN: Nefrología Supl. 3. 2008, 123-128.

  4. TRASPLANTE RENALANTICIPADO ¿ Quienes ? * Pacientes con ERCG5: Posibilidad de DVR. * Donante cadavérico: limitado. * ArzeAimaretti L, Arze S.: Preemptive Renal Transplantation: TheBestTreatment Optionfor Terminal Chronic Renal Failure. TransplantProc. 2016 Mar;48(2):609-11. * John J. Friedewald.: The Kidney-First Initiative: What Is the Current Status of Preemptive Transplantation? Advances in Chronic Kidney Disease, Vol 19, 2012: 252-256 * Prujim MT. et cols.: Preemptive versus Non-preemptivesimultaneouspancreas-kidney transplantation. Transplantation, Apr 2006.5.

  5. TRASPLANTE RENALANTICIPADO ¿ Cuándo indicar ? * EuropeanBestPractiseGuidelinesfor renal transplantation. Nephrol Dial Transplant 2000; 15 (12): 1897-2069. * Knoll G. et cols.: KidneyTransplantWorkingGroup of the Canadian Society of Transplantation. CMAJ 2005; 173: 1181-1184.

  6. TRASPLANTE RENALANTICIPADO * VENTAJAS * No Acceso vascular/Catéteres. * ↓↓ Gastos ͌ a diálisis. * Mejor QoL. * ArzeAimaretti L, Arze S.: Preemptive Renal Transplantation: TheBestTreatmentOptionfor Terminal ChronicRenal Failure. TransplantProc.2016 Mar;48(2):609-11. * Joo KW. et al: Preemptivetransplantation and long-termoutcome in living donorkidneytransplantation. TransplantProc 39:3061, 2007 * Meier-KriescheHU, Schold JD. The impact of pretransplant dialysis on outcomes in renatransplantation. Semin Dial. 2005;18:499-506. * Huang Y, Samaniego M.: Preemptive kidney transplantation: has it come of age? NephroTher. 2012 Nov;8(6):428-32.

  7. TRASPLANTE RENALANTICIPADO * VENTAJAS * > Supervivencia (injerto/paciente). * < % Tasa RA/RFI. * ArzeAimaretti L, Arze S.: Preemptive Renal Transplantation: The Best Treatment Option for Terminal Chronic Renal Failure. Transplant Proc. 2016 Mar;48(2):609-11. • * JooKW. et al: Preemptive transplantation and long-term outcome in living donor kidney transplantation. Transplant Proc • 39:3061, 2007 • * Meier-KriescheHU, Schold JD. The impact of pretransplant dialysis on outcomes in renal transplantation. SeminDial. • 2005;18:499-506. • * Huang Y, Samaniego M.: Preemptive kidney transplantation: has it come of age? NephroTher. 2012 Nov;8(6):428-32.

  8. TRASPLANTE RENALANTICIPADO * DESVENTAJAS (Donante Cadavérico) * Momento de inclusión en lista de espera (FG < 15 ml/min). * ↑↑ Tiempo de espera para TR de pacientes en diálisis. • * Morales Ruiz E.: Trasplante Renal Anticipado. Nefrología Supl. 3. 2008, 123-128. • * Birkelond SA. Uremia as a state of immunodeficiency. Scan J Immunol. 1976; 5: 107-115.

  9. TRASPLANTE RENALANTICIPADO * DESVENTAJAS (Donante Cadavérico) * > % de incumplimiento Tx. Mx. * Influencia de la uremia→→→ RA • * Morales Ruiz E.: Trasplante Renal Anticipado. Nefrología Supl. 3. 2008, 123-128. • * Birkelond SA. Uremia as a state of immunodeficiency. Scan J Immunol. 1976; 5: 107-115.

  10. TRASPLANTE RENALANTICIPADO ¿ Sería aplicable en nuestro medio ? • * VanrenterghemY, Verberckmoes. Pre-emptivekidneytransplantation. NephrolDial • Transplant1998; 13: 2466-2468.

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