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The immune response at mucosal surfaces is crucial for defense against pathogens. This study emphasizes the significance of gut-associated lymphoid tissue (GALT) in inducing an immune response to specific antigens, providing insights for developing mucosal vaccines. The research conducted by K. Hase and colleagues, published in Nature, unveils the role of GALT in eliciting targeted mucosal immunity, shedding light on mechanisms for enhanced immunization strategies.
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GP2 is important for the induction of an antigen-specific mucosal immune response. K Hase et al.Nature462, 226-230 (2009) doi:10.1038/nature08529