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This supplemental figure illustrates the impact of DMSO and U0126 treatments on the expression of key proteins in WM793 and WM115 melanoma cell lines. It focuses on the levels of BimEL, phosphorylated Bad (S75), and ERK1/2 proteins, providing insights into the apoptotic and signaling pathways affected by these compounds. The data highlights the differential responses of the cell lines to the treatments, contributing to the understanding of melanoma cell biology and potential therapeutic strategies.
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Boisvert-Adamo and Aplin Supplemental Fig. 1 WM793 WM115 DMSO DMSO U0126 U0126 BimEL p-Bad (S75) Bad p-ERK ERK1/2