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This chapter delves into the intricate processes of synthesizing conjugated dienes and their reactions, including 1,2- and 1,4-addition mechanisms. We will explore retrosynthetic analysis by working backwards from products to identify potential pathways. The synthesis plan includes showing forward reactions with appropriate reagents. Key topics include the preparation of dienes, polymerization processes, Diels-Alder reactions, and their applications in forming cyclohexenes. Understanding both kinetic and thermodynamic factors in these reactions is crucial for effective synthesis strategies.
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Synthesis problem Retrosynthetic analysis (work backwards from product) Synthesis plan (Show forward reactions with reagents)
Reactions of conjugated dienes 1,2- and 1,4 addition of HX and X2 Polymerization Diels Alder cycloaddition
Addition of HX to dienes kinetic thermodynamic
Addition of X2 to dienes kinetic thermodynamic
Diels-Alder Cycloadditions: one-step preparation of cyclohexenes