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Ontology of Experimental Variables and Values (OoEVV) Curation and Implementation

Explore the bottom-up curation of terminology for experimental variables using the Ontology of Experimental Variables and Values (OoEVV). Learn about the Science is Cyclic (CoSI) model, capturing experimental variables in context, and knowledge engineering from experimental design (KEfED). Discover the mathematical encoding of variables and measurement scales within OoEVV, along with software development and the OoEVV viewer.

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Ontology of Experimental Variables and Values (OoEVV) Curation and Implementation

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  1. Bottom-up curation of terminology for experimental variables: the Ontology of Experimental Variables and Values (OoEVV) Gully APC Burns, Jessica A Turner

  2. Science is Cyclic Cycles of Scientific Investigation (‘CoSI’ model) ☐ ☐☐☐ ☐☐☐☐☐

  3. Focus on Experimental Variables ‘CDNF protects nigral dopaminergic neurons in-vivo’ This statistically-significant effect is the experimental basis for the findings of this study. from Lindholm, P. et al. (2007), Nature, 448(7149): p. 73-7 Cycles of Scientific Investigation (‘CoSI’ model) ☐☐☐☐ ☐☐☐☐☐

  4. Capturing Experimental Variables in Context http://www.bioscholar.org/ Knowledge Engineering from Experimental Design (KEfED) ☐☐ ☐ ☐☐☐☐☐

  5. Knowledge Engineering from Experimental Design (‘KEfED’) Khan et al. (2007), J. Neurosci. 27:7344-60 [expt 2] Knowledge Engineering from Experimental Design (KEfED) ☐☐ ☐ ☐☐☐☐☐

  6. OoEVV Basic Design Mathematical encoding of the variable Quality being measured (conceptual, no encoding) Variable measuring the quality 1 1 * * Scale Quality Variable ‘Handedness’ Simple-handedness-category [‘left’, ‘right’, ‘ambidextrous’] Edinburgh-handedness-score [ -100 … +100 ] Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  7. OoEVVImplementation Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  8. Measurement Scales Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  9. Software Development Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  10. OoEVVSoftware http://www.isi.edu/projects/ooevv/ooevv_software Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  11. OoEVV Viewer Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  12. Acknowledgements BMKEG@ISI Marcelo Tallis Drashti Dave Ed Hovy Biomedical Informatics Research Network (BIRN) Joe Ames Jose Luis Ambite Naveen Ashish Funding FBIRN: RR021992 BIRN: RR025736 CogPO: MH084812 BioScholar: GM083871 Thank you for listening!

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