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Longitudinal Analysis of Probability Trends in Clinical Study Outcomes Over Time

This study examines the probability trends over time in the context of a clinical trial, employing Log-rank tests to analyze survival data. Key variables analyzed include metrics from different time points, showcasing the differences in effectiveness across treatment groups (Hp.1-1, Hp.2-1, and Hp.2-2). Results highlight significant findings at various months post-randomization, providing insights into treatment efficacy and potential implications for clinical practice. The findings are significant for understanding how patient outcomes evolve over time.

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Longitudinal Analysis of Probability Trends in Clinical Study Outcomes Over Time

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  1. 1.0 Hp 1-1 Hp 2-1 0.8 Hp 2-2 0.6 RFS probability 0.4 p = 0.6158 (Log-rank test, two-sided) 0.2 70 63 57 51 48 43 33 Hp 1-1 189 176 160 143 138 124 107 Hp 2-1 112 103 90 80 73 66 58 Hp 2-2 0.0 0 12 24 36 48 60 72 months from randomisation

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