1. Yale Center for Clinical Investigations Public Communication Approaches & Best Practices Communications Key Function Committee Face-to-Face Meeting Rockville MD, April 1, 2009

2. WORKING STRATEGIES: • Recruitment web-site • Targeted Mailing • Print Media: • Public Brochures • Newsletter • Billboards • Public Transportation • Commuter Train • Buses • Community Event Booths • Public Service Announcements • TV • Radio Best Practices: YCCI Public Awareness Campaign

3. Recruitment EffortsVolunteer and Recruitment Web-pagehttp://yalestudies.org/orhttp://yaletrials.org/or http://y-studies.org Help Develop the Medicine of Tomorrow

4. Public Events: Volunteer Appreciation Day

5. CARE News Letter Sent out quarterly Permission-based mailing Linked to YCCI web-site

6. General Public Awareness: Billboards

7. Transportation: Communicating the importance of clinical research through past successes Help Yale Develop the Medicine of Tomorrow Like many discoveries, the development of the first insulin pump was a combination of ingenuity and teamwork. In 1979, Yale doctors were conducting studies to figure out the best way to deliver insulin to diabetic children. They discovered that giving small amounts continuously with larger doses at meals worked better than giving one large dose, because this more closely resembles the way the pancreas produces insulin. Like many discoveries, the development of the first insulin pump was a combination of ingenuity and teamwork. In 1979, Yale doctors were conducting studies to figure out the best way to deliver insulin to diabetic children. They discovered that giving small amounts continuously with larger doses at meals worked better than giving one large dose, because this more closely resembles the way the pancreas produces insulin. Unfortunately, there was no easy way to accomplish this. Around the same time, another Yale doctor was using a portable pump to help solve a different problem: delivering medicine to children who had a dangerous buildup of iron due to frequent blood transfusions. Dr. Bill Tamborlane, Dr. Bob Sherwin and their colleagues realized this pump would be ideal for applying what they had learned about insulin delivery to their patients. The insulin pump was first tested in seven diabetic children and the results were spectacular. Dr. Tamborlane remembers staying overnight in the hospital so that he could monitor the results. When he began to see that blood sugar levels remained stable in his young patients, he knew that he and the other Yale doctors had hit upon a novel and effective treatment for diabetes. The insulin pump, which today has evolved into a device the size of a beeper, continues to gain momentum; last year 350,000 diabetics used it and its popularity continues to grow. Without volunteers like the children and their families who were willing to take a chance on an exciting new treatment, this groundbreaking discovery would not have been possible.

8. Local County Fair: Information Booth

9. Targeted Mailing

10. Public Service Announcement: TV • Narrative feature of Dr. Bob Sherwin and Dr. Bill Tamborlane speaking about the first clinical use of the insulin pump.  • Aired on WTNH Channel 08, Apr 28th - May 4th the air time frames are below. • Mon - Fri   6-9 am   10 times during the week during Morning news and Good Morning America • Mon - Fri   12-1pm   5 times during the week during News Channel 8 • Mon - Fri   4-5 pm    5  times during the week during Judge Judy • Mon - Sun   5-6:30 pm    10  times during the week News Channel 8 • Sat - Sun   6-9 am   6 times during the week during Weekend Morning news