1 / 31

-sheet

-sheet. 2 peptide backbones Very open configuration "Pleated" Parallel and antiparallel. Tertiary Structure. Thermodynamically most stable form Held together by Hydrophobic interactions Electrostatic interactions -S-S- bonds Can include non-protein groups

kenton
Télécharger la présentation

-sheet

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. -sheet • 2 peptide backbones • Very open configuration • "Pleated" • Parallel and antiparallel

  2. Tertiary Structure • Thermodynamically most stable form • Held together by • Hydrophobic interactions • Electrostatic interactions • -S-S- bonds • Can include non-protein groups • Prosthetic groups or co-enzymes • Determined by x-ray crystalography

  3. Types of Tertiary Structures • Fibrous proteins • Silk • Keratin • Collagen • Globular proteins

  4. Quaternary Structure

  5. Carbohydrates (saccharides)

  6. Monosaccharides • Polyhydroxy aldehydes or ketones • Aldoses—aldehyde on end • Ketoses—ketone in chain

  7. Monosaccharides, con't. • Named by number of carbons • Trioses • Tetroses • Pentoses • Hexoses • Heptoses

  8. Glucose • 4 chiral carbons • "D" configuration • Fischer projection

  9. Ring formation

  10. Chair configuration

  11. Aldohexoses

  12. Monosaccharide derivatives

  13. Fructose

  14. Glycosidic bonds

  15. Polysaccharides

  16. Types • Storage • Starch • Glycogen • Structural • Cellulose • Chitin • Extracellular matrix

  17. Storage • Glucose in (14) linkages • Amylose—10-30% • unbranched • Amylopectin—70-90% • Branched every 12-25 residues • (16) linkages • Glycogen • Branched every 8-12 residues

  18. Glycogen

  19. Structural • Cellulose • Glucose • (14) linkages • No branches • Most abundant macromolecule

  20. Structural, con't. • Chitin • N-acetyl glucosamine • Second most abundant macromolecule • Bacterial cell wall • peptidoglycan

More Related