Food Safety & Environmental Seminar

1. Food Safety & Environmental Seminar • The Sebel Hotel, Cairns Australia • 26th August 2012

2. One year on…. Cairns in Winter

3. What a difference a year makes.... SuperVap Family of solvent concentrators PowerPrep SPE Automated Parallel SPE

4. What a difference a year makes.... Trace 1300 GC iCAP Q ICP-MS TSQ 8000 GC-MS/MS Q Exactive LC-MS/HRMS ExactFinder Screening and Quantification TargetQuan 3 POPs Quantification

5. New for DFS • TriPlus RSH + • Trace 1310 GC + • TargetQuan 3 New technologies for modern POPs analysis

6. TRACE 1300 series • Modular • Flexible user changeable injector and detector modules • Small • 33% smaller than 7890 • Fast • Fast heating and cooling due to low thermal mass • Familiar • Common SSL consumables to 7890 • Simple • Touch screen UI in any language

7. Trace 1300 - Instant Connect Modules Pneumatic control • Modules incorporate: • Injector (or detector) body and heater • Gas control Valves • Electronics for temperature and gas control, for signal amplifier and A/D conversion Inlet/ detector body Specific electronic control boards Electronic boards Proportional solenoid valves for gas control Pneumatic manifold Inlet body heater and Insulation GC oven Column connection (inside the oven)

8. Trace 1300 Series – Injector Modules • Injector modules include injector body, valves, filters, electronics for temperature and carrier gas control • SSL, PTV, LVI, On-Column • Backflush integrated • SSL specially designed • Cool head and septum • Lower septum bleeding • Longer septa lifetime for high productivity • No septum sticking for quick maintenance • Uniform temperature along liner • Tubing-less injector • Lower air (oxygen) diffusion • Column lifetime and MS sensitivity preserved • Same consumables as 7890 – simple method transfer Robust, repeatable and reliable injector performance

9. TriPlus RSH – Robotic Sample Handling

10. TriPlus RSH – Robotic Sample Handling • Automated tool exchange • Vial bottom detection • Sample preparation • Dilution • Mixing • Derivatisation • Calibration Curves • Standard Spiking • SPME, Headspace, Liquid Powerful versatility in sample handling and injection

11. TriPlus RSH: Substantially Reducing $/sample Lab Cost • Automated basic sample handling and sample prep • Calibration dilution: automatically prepare calibration points adding internal standards Labor costs strongly reduced while improving accuracy ISTD

12. TriPlus RSH: Higher quality results and performance • Accurate injection from microvolume samples – • Ideal for trace POPs analysis • Biological fluids, • or when an expensive external standard is used • New bottom vial sensing capability • Delivers accurate and reproducible injections • Sample as low as 5 µL

13. TriPlus RSH - Inject from low volumes • 5 µL sample in vial • 5 replicates of 1 µL • Vial bottom sensing option 3 replicates possible with 5 µL sample: average RSD 1%

14. TargetQuan™ 3

15. What does TargetQuan 3 do? • Advanced data processing and quantification for target compounds: • MS • MS/MS • HRMS • Comprehensive QA/QC checks • Full audit log • Reports to PDFs or exports to text, spreadsheet, LIMS • Quantifies complex data sets, quickly and efficiently

16. 1. Analyse Samples - MS, MS/MS or HRMS

17. 2. Open Sequence

18. 3. Process Sequence

19. 4. Review Data

20. 5. Report data

21. 6. Save data

22. Report, Archive, Audit All data are saved in one file for simple traceability

24. Food Safety & Environmental Seminar • The Sebel Hotel, Cairns Australia • 26th August 2012

25. Agenda

26. Agenda

27. SAVE THE DATE 7th Thermo Fisher Scientific Symposium on Recent Advances in POPs analysis • Thursday 11th April 2013 • Hilton Hotel • San Francisco • In collaboration with • Fluid Management Systems Inc. • BFR 2013