TRADITIONAL AND COMPLEMENTARY MEDICINE IN CANCER MANAGEMENT

1. TRADITIONAL AND COMPLEMENTARY MEDICINE IN CANCER MANAGEMENT Prof. Julius W. Mwangi E.B.S. Julius.mwangi@uonbi.ac.ke 6th KEMRI Annual Research Health Conference, 9th -11 Feb, 2016

2. EXAMPLES OF TRADITIONAL /COMPLEMENTARY MEDICINE? • HERBAL MEDICINE • Homeopathic • Aromatherapy • Ayurved • Acupuncture & moxibustion • Traditional Chinese Medicine • Reflexology • Massage • Yoga • Chiropractic • Laughter • Naturopathy • Urine therapy • Pet

3. Traditional and Complementary Medicine There are over one hundred practicesworldwide. Some not widely used. Some not well understood. Some confused with witchcraft.

4. SOURCE OF MODERN MEDICINES

5. CANCER DRUGS IN CLINICAL USE/TRIALS FROM PLANTS • Vinblastine/Vincristine :Madagascar - leukaemias, lymphomas and some solid tumours • Etoposide: US, Himalayas – refractory testicular tumours; lung cancer • Paclitaxel/Docetaxel: Europe – ovarian cancer • Topotecan/Irinotecan: China – Ovarian cancer • Omacetaxine/Homoharringtonine: Japan - chronic myeloid leukemia • Flavopiridol: India -cyclin-dependent kinase inhibitor -refractory chronic lymphocytic leukemia • Combretastatins: S. Africa - advanced cancer refractory to standard therapy

6. KENYA • Kenyans -Irrespective of their social status, ethnic group or religion regularly use T & C M • Studies have shown that use is not a sign of: - Uninformed and underprivileged rural poor Who is using T&C M in cancer management in Kenya ?

7. WHO ELSE IS USING THIS MEDICINE TO MANAGE CANCER?

8. Thailand The prevalence of use was 60.9%. Most frequently dietary/vitamin supplements (56.9%). high income and cancer type Half of the patients reported positive effects Majority of patients did not disclose use of CAM to their doctors

9. Europe • Europe: T&C very popular with cancer patients • Usage TRIPLED after diagnoses • Many seemed to have benefited • Younger people, female and with higher educational level. • Europe 36 % • 47%–Norwich, UK

10. Germany Administered alongside standard therapy to 35% of children with cancer in Germany higher social status and poor prognosis physical stabilization, strengthening the immune system and improving the chance of cure 89% of the users reported that they would recommend CAM to other parents

11. Other Developed coutries? USA 40% Canada 43% New Zealand 49% Japan 44.6%

12. Zanthoxlum, MUKENEA, MUBUCUA, SHIKHUMA, SAGAWAITA, NDUMGU

13. Emotoe , Mhulapori, Chepterekiat, Murubae Mtemua , shamba, Idigaga, Lopotwo, Ol-assaiyet , Ofuyaendwa,Ashwagandra Indian ginseng (Withania somnifera)

14. FOOD FOR CANCER PREVENTION? • Anti-Angiogenesis Metronomic therapy • new approaches by attacking the tumor’s blood supply thus depriving it food. • administering comparatively low doses of drug on a frequent or continuous schedule, with no extended interruptions . • Bevacizumab – FDA approved

15. FOODSAnti-Angiogenesis Metronomic therapy? • Cabbage family: Broccoli, Brussels Sprouts, Cauliflower, Kale, cabbages . Also Spinach and Beet Root • Rectal and colon cancer • Unskinned tomatoes: Cancer of stomach & prostate- • “A clove of garlic a day keeps the doctor away”.Alliumsativum – Garlic, Leeks, Yellow and Green Onions, • Breast cancer, brain cancer, lung cancer, pancreatic cancer, prostate cancer, childhood brain cancer, colon and stomach cancer. • Citrus , blueberries, pomegranate , grapes • Turmeric • Soybean • Camellia sinensis -tea

16. Conclusion WE SHOULD BE INTERESTED IN USE OF TRADITIONAL AND COMPLEMENTARY MEDICINE IN CANCER MANAGEMENT BY OUR PEOPLE.

17. THANK YOU