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Lock and Key Model

Lock and Key Model. Objectives Define the Lock and Key Model 2. Provide specific examples of how the lock and key model is used 3. Describe how scientists use this information to create new therapies and drugs. Lock and Key Model Defined.

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Lock and Key Model

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  1. Lock and Key Model Objectives Define the Lock and Key Model 2. Provide specific examples of how the lock and key model is used 3. Describe how scientists use this information to create new therapies and drugs

  2. Lock and Key Model Defined • Molecules have a shape that only fits specific receptors • Ex. Square peg only fits into square hole, star peg only fits into star hole

  3. Enzymes • Proteins in the body that assist chemical reactions to occur and/or occur faster than they normally would http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter2/animation__how_enzymes_work.html

  4. Communication • Cells communicate with one another by releasing chemicals. • These chemicals bind to receptors on the surface of other cells • The chemicals may be delivered to nearby cells or cells across the body (using the blood stream) • When the lock and key is formed, the message has been sent http://www.youtube.com/watch?v=U6uHotlXvPo

  5. Determining “Self” from Invaders • Your bodies immune (defense) system needs to be able to determine what is “self” and what is an invader • It uses the lock and key method to determine invaders from self http://www.youtube.com/watch?v=cL9KY_ECzfo

  6. Using Lock and Key Model in Therapies • Scientists create drugs that mimic (look like) messenger molecules • These messenger molecules may activate the response • Or the molecule may fit, but not perfectly, so the hole is blocked and the message CANNOT be seng

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