10 likes | 187 Vues
Suppl.C. GFP. GAP-43. merge. Sustained activation of ERK pathway induces neurite outgrowth in TNB-1 cells
E N D
Suppl.C GFP GAP-43 merge Sustained activation of ERK pathway induces neurite outgrowth in TNB-1 cells TNB-1 cells were transfected with the indicated pCDNA3-derived Raf constructs and the pEGFP-C3 reporter construct. Expression of activated Raf protein, RafCAAX, induced neurite outgrowth in TNB-1 cells. RafCAAX : full-length Raf1 proteins containingcarboxyl-terminal fusions with the membrane localizationsequences of Ki-ras. RafS621A: dominant negative form of Raf1. Vec Raf CAAX Raf S621A