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Understanding the Two Arms of Adaptive Immunity: Antibody-Mediated and Cell-Mediated Responses

This lecture explores the key components of adaptive immunity, focusing on the two primary mechanisms: antibody-mediated and cell-mediated responses. Antibody-mediated response involves B cells producing antibodies that specifically target antigens, while cell-mediated response includes cytotoxic T lymphocytes (CTL) and natural killer (NK) cells that act against infected or altered host cells. We discuss how B cells can also activate phagocytes and how some pathogens evade detection by hiding within host cells, triggering a complex immune response.

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Understanding the Two Arms of Adaptive Immunity: Antibody-Mediated and Cell-Mediated Responses

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Presentation Transcript

  1. Lecture 9Immunity

  2. Two Arms of Adaptive Immunity • Antibody-mediated response • Cell-mediated response • Some cells activated B cells or phagocytes: • B cells will produce antibodies that can bind with specific antigen-bearing particles • Some are able to hide in host cells or only briefly found outside the cells circulating: • Alters the host cells • Activates cell-mediated immune response • Involves CTL and NK cells

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