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How Cells Harvest Energy: Chapt. 7

How Cells Harvest Energy: Chapt. 7. food substances are energy-rich molecules cells oxidize food to release energy. Oxidation. removal of electrons (often as hydrogen atoms) as one molecule is oxidized another is reduced (Red-Ox reactions) Text pg 116. + electron.

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How Cells Harvest Energy: Chapt. 7

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  1. How Cells Harvest Energy:Chapt. 7 • food substances are energy-rich molecules • cells oxidize food to release energy

  2. Oxidation • removal of electrons (often as hydrogen atoms) • as one molecule is oxidized another is reduced (Red-Ox reactions) • Text pg 116 + electron oxidized reduced (electron acceptor) (electron donor)

  3. Cellular Redox Reactions • Typically Exergonic reactions • DG is negative • Reactants Products + E. • E. (in the form of e-) is used for initiating other reactions

  4. Cell Oxidation-ReductionReactions Performed by: • Cell molecules such as NAD, NADP, FAD, FMN …termed coenzymes • each of these work with specific enzymes to catalyze redox reactions • Text pg 116 • when reduced (ie. NADH, NADPH) each gains energy for use elsewhere in the cell

  5. Storage Sources of Cell Energy: • Triglycerides (fats) • Carbohydrates (glycogen, starch) Both end up following the breakdown pathway for glucose.....

  6. Glucose Breakdown-an oxidation process Occurs as two separate processes: 1. Glycolysis 2. Cellular respiration

  7. 1. Glycolysis • occurs in cytoplasm • evolutionary primitive energy creating system • may occur in anaerobic environments Summary: One (6-carbon glucose) goes to form Two (3- carbon pyruvate) molecules produces 2 ATP & 2 NADH Low energy yield (~3% Potential)

  8. Glycolysis + (2) Pyruvate Glucose

  9. Glycolysis Energy Yield ~700 Kcal of energy stored in 1 glucose sugar... Glycolysis produces 2 ATPs from glucose Each ATP is worth ~7-10 Kcal Therefore, ~20 Kcal produced 20/700 = ~3% efficiency

  10. Glycolysis: Part 1- Uses ATP Energy Glucose (6C) Glyceraldehyde 3-phosphate (3C) 2 ATP 5 Steps 2 ADP

  11. Glycolysis: Part 2- Generates ATP + NADH G3P (3C) Pyruvate (3C) 4 ADP 2 NADH 4 ATP 5 Steps

  12. Gylcolysis

  13. Glycolysis: Summary • 10 enzymes act in sequence to: • Convert 1 Glucose (6C) --> 2 Pyruvate (3C) • 2 ATP’s produced • 2 NADH produced • Reactions occur in cytoplasm

  14. When Oxygen is available to the cell, glycolysis is followed by cellular respiration… • Text pg 117 • When O2 is unavailable, glycolysis will lead to Fermentation steps… • Text 117

  15. Fermentation When inadequate oxygen is present, for example, in a muscle cell undergoing vigorous contraction, the pyruvate produced by glycolysis is converted to lactate. This reaction uses NADH produced in glycolysis, and the whole pathway yields much less energy overall than complete oxidation.

  16. Fermentation In some organisms that can grow anaerobically, such as yeasts, pyruvate is converted via acetaldehyde into carbon dioxide and ethanol. Again, this pathway regenerates NAD+ from NADH, as required to enable glycolysis to continue.

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