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1. Diabetic Foot UlcersEvidenced Based Practice Kendra Round, R.N.
Northeastern State University
EBP Symposium
April 23, 2010
kd_round@hotmail.com
2. Background
Jack C. Montgomery VA Medical Center, Muskogee
7,500 lower limb amputations annually in FY 1989-1991
5,180 veterans discharge with amputations in 1992
Preservation Amputation Care and Treatment (PACT) program
Fotieo, Reiber, Carter, & Smith, 1999, p. 55
Mayfield, Reiber, Maynard, Czerneicki, Caps, Sangeorzan, 2001, p. 342
Robbins, 2007, p. 161
3. PICO Question
Among patients with diabetic foot ulcers, will those who have oasis wound treatment, as compared to those who use pulsed radio frequency energy, experience improved wound healing time?
4.
Chronic skin breakdown is a significant clinical problem that has been described as a silent epidemic.
Grocott & Campling, 2009, p. 28
5. Significance of the Problem 23. 6 million people, or 7.8% of the population have diabetes
More than 60% of nontraumatic lower-limb amputations occur in people with diabetes
An estimated 57 million people in the U.S. have prediabetes
The total estimated cost of diabetes for direct and indirect medical cost is $174 billion
Centers for Disease Control, 2008, www.cdc.gov
Dall, Mann, Zhang, Quick, Seifert, Martin, Huang, & Zhang, 2009, p. 157
6. A large portion of foot ulcers fail to heal in spite of months of treatment and they develop into chronic wounds when healing stops which leads to complications such as infections which in turn lead to amputation.
Rando, 2009, p. 70
7. Extracellular matrix (ECM) and cellular proliferation
ECM
Physically support and orient cells
Regulate cellular properties
Regulate growth factor function
Chokan, 2007, p. 122
8. ECM not only supports cell migration but activate cells to replicate, activate and bind growth factor.
In hard to heal wounds, ECM cannot support healing due to systemic abnormalities such as diabetes.
Chokan, 2007, p. 122
9. OASIS Biological extracellular matrix made from porcine small intestine
Components
Collagen
Fibronectin
Glycosaminoglycans
Proteoglycans
Chokan, 2007, p. 122
10. OASIS Provides and ECM for hard to heal wounds
Stimulates
Cellular adhesion
Improving cellular motility
Some growth factors
Recurrent, chronic wounds or wounds that have failed standard care
Chokan, 2007, p. 128
11. OASIS Debridement before application
Apply weekly
Each application will lead to new epithelialization
16 week study
Chokan, 2007, p. 128
Romanelli, Dini, Bertone, & Brilli, 2007, p. 5
12. OASIS $250 per patient for 12 weeks
Store at room temperature
Reabsorbed by the body
Contraindications
Sensitivity to porcine material
Third degree burns
13. Pulsed Radio Frequency Energy (PRFE)Provant Therapy System
Cell proliferation induction (CPI)
27.12 MHz frequency
Applicator pad
30 minutes twice per day
Frykberg, 2009, p. 45-46
14. PRFE - Provant
Frykberg, 2009, used Provant on 5 patients for 12 weeks which closed the wound and kept the wound closed for several months.
15. PRFE - Provant Short-wave diathermy
Survey to determine clinical and safety practices
Beneficial in management of soft tissue injuries
Did not exacerbate other conditions
Preferred treatment
16. PRFE- Provant Easy to use
Non-invasive
Confidential cost analysis
$88 per patient/per day
Contraindications
Treatment of deep tissue and bone
Metallic implants in area of application
Cardiac pacemakers
Pregnancy
Immature bone development
Implanted lead
17. Approach to Problem
Comparable healing times
Cost
Application
Contraindications
Recommendation based on evidence
Oasis wound treatment
18. Leadership Support Podiatrist and Wound Care Specialist
Oasis
Staff training
PACT program
19. Evaluation Education on PACT program
Wound Care Champions
Tracking for further changes
20. QUESTIONS?