Biotechnology manipulates living things to make useful products.

1. Biotechnology manipulates living things to make useful products. http://www.youtube.com/watch?v=OcG9q9cPqm44:41 “The Invisible Revolution” biotechnology 1. What are the “ethical” issues? - Agriculture - Industry/manufacturing 2. How do each affect the economy? - Medicine - Environment 3. What affect does biotechnology have - Energy - Careers on careers that are available? ************************************************************************************************ • Aspects of biotechnology include: - specific genetic information available - careers - ethical issues - implications for agriculture - economic benefits to North Carolina Examples: Circle each one on your study guide. • Crossbreeding • Selective Breeding • Genetic Modification • Cloning • Bioremediation

2. Three Basic Kinds of Biotechnology Tools • Working with Cells: - stem cells 2. Working with Proteins - protein coat on cells 3. Working with Genes - genetic engineering

3. Crossbreeding: two different kinds/breeds of organisms are bred together Examples: Tiger + Lion

4. Liger (infertile)

5. Donkey + Horse A donkey and a horse will produce offspring called a ___________.

6. Mule (infertile) What are the advantages and disadvantages of cross breeding?

7. Selective Breeding: the intentional mating of organisms to produce offspring with specific traits • Examples: • cows that have been observed producing large volumes of milk; • breeding to pass traits on to ensuing generations have similar traits • race horses bred for speed, distance • dogs bred for particular traits (color, size, temperament, hypoallergenic)

8. The Australian Dinghound Originated in New Zealand, these dogs were used to herd sheep. They were brought to Australia in 1857 by Sir Sidney Melbourne. The Australians, not needing another breed of shepherd dog, bred the dogs with wild Dingoes. The result was a new breed of large shaggy black dogs with unusual spotted markings. The Australians used the new breed to guard houses. Dinghounds proved valuable as watchdogs because of their ability to sense danger as well as insincerity. What advantages are there to selective breeding? Selective Breeding in Dogs

9. Selective Breeding: Wolf Ancestors What are the advantages and disadvantages of selective breeding?

10. Genetic Modification: changes the genetic material of a living organism • Medicines • Treatment of Diseases • Vegetables • Fruits Ethical Issues http://www.youtube.com/watch?v=cPa8Vxqvkn0 spider and sheep

11. Put these examples in your notebook.  What are some of the advantages of GM foods?  Pest resistance (insecticides) Herbicide tolerance  Disease resistance  Cold tolerance (see WXII news segment)http://www.wxii12.com/news/local-news/piedmont/farmers-perpare-for-jack-frost/-/10703612/22599854/-/1034po8/-/index.html?absolute=true Drought tolerance/salinity tolerance  Nutrition

13. Continued: Advantages of GM Products •  Pharmaceuticals: edible vaccines in tomatoes and potatoes; much easier to ship, store and administer than traditional injectable vaccines. •  Phytoremediation: Plants such as poplar trees have been genetically engineered to clean up heavy metal pollution. What are the advantages and disadvantages of genetic modifications?

14. What do you think? Pros & Cons of GM Foods

15. GM Foods In U.S. • Corn - Strawberries • Soy bean - Zucchini • Sugar cane - Pineapples • Tomatoes - Cocoa Beans • Potato - Yellow Squash • Sweet Potatoes - Bananas Genetically modified cows can produce lactose free milk.

17. Cloning: three types of cloning technologies are:(This information will not be on your test. ) • recombinant DNA technology or DNA cloning (2) reproductive cloning (3) therapeutic cloning (embryo cloning) What are the ethical Issues?

18. (1) recombinant DNA technology or DNA cloning(This information will not be on your test. ) • transfer of a DNA fragment of interest from one organism to a self-replicating genetic element such as a bacterial plasmid • DNA of interest can then be reproduced in a foreign host cell What are the ethical Issues?

19. Dolly, the first mammal to be cloned from adult DNA, died at age 6. Dolly or any other animal created using nuclear transfer technology is not truly an identical clone of the donor animal. Dolly was only one success out of 276 tries. (2) reproductive cloning (This information will not be on your test. )

20. used to generate an animal that has the same nuclear DNA as another currently or previously existing animal. - The reconstructed egg containing the DNA from a donor cell must be treated with chemicals or electric current in order to stimulate cell division. - Once the cloned embryo reaches a suitable stage, it is transferred to the uterus of a female host where it continues to develop until birth. (This information will not be on your test. ) What are the ethical Issues?

21. (This information will not be on your test. ) (3) therapeutic cloning (embryo cloning) goal is not to create cloned human beings, but rather to harvest stem cells that can be used to study human development and to treat disease. Stem cells are important to biomedical researchers because they can be used to generate virtually any type of specialized cell in the human body. - Many researchers hope that one day stem cells can be used to serve as replacement cells to treat heart disease, Alzheimer's, cancer, and other diseases. What are the ethical Issues?

22. Biotechnology Applications to the Environment Bioremediation: the completely safe and natural process of cleaning up organic contaminants through the use of microbes (i.e. bacteria). Sewage spills Oil spills Gasoline contamination Toxic waste spills

23. Bioremediation

24. Bioremediation Before and After

25. Biotechnology & Energy • Biomass fuels: - eliminates harmful emissions - renewable source of energy - reduces our dependency on fossil fuels and other countries that supply them - fewer contaminants enter waterways

27. Duke Energy & Duke University: methane project