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New Year’s Launch of Six New Technologies for Veterinary Clinical Pathology

New Year’s Launch of Six New Technologies for Veterinary Clinical Pathology. Hematology – Maureen McCullaugh Blood Gas Analysis – Mick Garrett Endocrinology – Joel Eluk, Penny Furney Flow Cytometry – Inese Berzina, Amanda Lawler, Emma O’Neill

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New Year’s Launch of Six New Technologies for Veterinary Clinical Pathology

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  1. New Year’s Launch of Six New Technologies for Veterinary Clinical Pathology Hematology – Maureen McCullaugh Blood Gas Analysis – Mick Garrett Endocrinology – Joel Eluk, Penny Furney Flow Cytometry – Inese Berzina, Amanda Lawler, Emma O’Neill Multiplex Immunoassay – Marianna Serra, Penny Furney Cellomics – Margarida Domingos

  2. Novel State-of-the-Art Biomarker Technologiesat UCD UVH Immunology Hematology Cellomics Advia InCell Guava Immunochemistry Blood Gas Analysis Immunochemistry Centaur MSD RapidLab 1200

  3. Multiparameter Hematology System: ADVIA 2120 • Biggest advance in hematology technology for a generation in sensitivity, specificity and parameters added • Applicable to other body fluids eg effusions, BALF, CSF, & BM. Novel parameters eg reticulocyte size, maturity & Hb (most sensitive measure of Fe status), of platelet size & activation, of neutrophil myeloperoxidase, & of extracellular versus intracellular Hb • Managed by Maureen McCullaugh

  4. RapidLab 1200: Blood Gas Analyser • latest model in market place • delivers results for all parameters in 1 min • maintenance-free, cartridge-based system • LIMS interfaceable • Microsampler – as little as 30 uL • Comprehensive analytic panel: blood gas (pH, pCO2, pO2); electrolytes (Na+, K+, Ca++, CI- ); Metabolic (glucose, lactate) • Managed by Mick Garrett in out-of-hours / student lab Sample Port: Automatic sampling with a single port for syringe and capillary samples. Complete with automatic clot detection and clearance, short sample and bubble detection. Can backflush to clear so don’t have to replace cartridge.

  5. Centaur CP • automated Immunoanalyzer • latest model in market place • replaces Immulite • Numerous Parameters • Thyroid T4, T3, TSH • Reproductive eg progesterone, estradiol, testosterone • Adrenal eg Cortisol (dog) • Cardiac eg troponin, CK-MB (dog, horse) • Vit B12 and folate • Insulin • Skeletal Muscle troponin • Managed by Joel Eluk and Penny Furney

  6. Guava – Personal Flow Cytometer • smallest and easiest to use in marketplace • 2-angle scatter, 4 color • being developed for use for immunophenotyping of lymphoma and leukemia • Assessment of cell viability • Managed by Inese Berzina, Amanda Lawler, and Emma O’Neill

  7. MSD 2400 • automated mulitplexing immunoanalyzer • latest model in market place • for high throughputting, needing microvolume testing (25 uL vs 150 uL), needing mutliplexing • assay development possible • panels of mulitple cytokines and chemokines • cardiac panel of biomarkers • reproductive hormones • Managed by Marianna Serra, Penny Furney

  8. High Content Analysis & Hormesis ♦ Automated microscopy ♦ 96-well plate in incubator ♦ Live-cell, image analysis ♦ Single cell, populations, well l ♦ Real-time, kinetic, multiplex ♦ Intracellular location ♦Structure & function ♦Managed byMargarida Domingos

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