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CARBOHYDRATE METABOLISM

CARBOHYDRATE METABOLISM. Kadek Rachmawati, M.Kes., Drh. Content of lecture. 1. Structure of carbohydrate 2. Carbohydrate digestion 3. Carbohydrate metabolism. Goal of lecture. 1. To understand the structure of carbohydrate 2. To understand carbohydrate digestion

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CARBOHYDRATE METABOLISM

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  1. CARBOHYDRATE METABOLISM Kadek Rachmawati, M.Kes., Drh

  2. Content of lecture • 1. Structure of carbohydrate • 2. Carbohydrate digestion • 3. Carbohydrate metabolism

  3. Goal of lecture • 1. To understand the structure of carbohydrate • 2. To understand carbohydrate digestion • 3. To understand carbohydrate metabolism

  4. CARBOHYDRATE • Carbohydrate are aldehyde or ketone derivates 1. Monosaccharides * those carbohydrates that cannot be hydrolyzed into simpler carbohydrate * Classified as trioses, tetroses, pentoses and hexoses * Also classified as aldoses or ketoses

  5. Classification of simple sugar Aldoses Ketoses • Trioses Glycerose Dihydroxyacetone • Tetroses Erythrose Erythrulose • Pentoses Ribose Ribulose • Hexoses Glucose Fructose

  6. L-glucose and D-glucose Glucose

  7. Ketose group

  8. 2. Disaccharides * condensetion products of two monosaccharides * Ex. : - Sucrose : condensation of glucose and fructose - Lactose : condensation of glucose and galactose - Maltose : condensation of two glucose

  9. 3. Oligosaccharides : - condensation of three – six monosaccharide - exp : Maltotrioses 4. Polysaccharides : - > 7 monosaccharides - exp. Amylum/Starch Glycogen glucose polymer Dextrins Cellulose

  10. AMYLUM : - Most abundant dietary carbohydrate in cereals, potatoes, legumes and other vegetable - Two main constituent are : 1. Amylose nonbranching helical structure 2. Amylopectin α1,4-glucosidic linkage and α1,6-glucosidic linkage at branch point • GLYCOGEN - Storage polysaccharide in animal, at muscle and liver cell - More highly branched structure than amylopec- tin

  11. CELLULOSE * Insoluble * Linked by β-1,4-glucosidic, straight chains strengthened by cross-linked hydrogen bond * Cannot be digested by mammals * Constituent of the framework of plants

  12. Amylum : A. Amylose, B. Amylopectin

  13. AMYLOPECTIN IN AMYLUM

  14. A. Glycogen, B. Α-1,4-glucosidic linkage

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