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Empirical Model of CSF Flow

This document explores recent advancements in understanding the dynamics of cerebrospinal fluid (CSF) flow, particularly focusing on the effects of hydrocephalus on brain extracellular compartments. It reviews the role of active transport in eliminating substances from the CSF and highlights the relationship between intracranial pressure and CSF distribution. Key studies discuss transventricular and transpial absorption into cerebral microvessels, as well as osmotic control of intracranial pressure, providing a comprehensive overview of the hydrodynamics of CSF.

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Empirical Model of CSF Flow

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  1. Empirical Model of CSF Flow Ian Gopal Gould UIC – LPPD January 27, 2011

  2. M R Del Bigio and T L Enno, Effect of hydrocephalus on rat brain extracellular compartment.

  3. Vladic et. al., Homeostatic role of the active transport in elimination of 3H-BP out of the CSF

  4. Vladic et. al., Homeostatic role of the active transport in elimination of 3H-BP out of the CSF

  5. The effects of intracranial pressure on HRP transport Nebeshima, S., et al. Junctions in the meninges and marginal glia.

  6. Bulat, M., Klarica M., 2011. Recent insights into a new hydrodynamics of the cerebrospinal fluid. Brain Research Reviews. 65, 99-112. Bulat, M., Lupret, V., Orešković, D., Klarica, M., 2008. Transventricular and transpial absorption of cerebrospinal fluid into cerebral microvessels. Coll. Antropol. 32 (Suppl 1), 43–50. Bulat, M., Klarica, M., 2001. Osmotic control of intracranial pressure. Period. Biol. 103, 293–296. Del Bigio M.R., Enno T.L., 2008. Effect of hydrocephalus on rat brain extracellular compartment. Cerebrospinal Fluid Res. 2008 Jul 10;5:12. Nebeshima, S., Reese, T.S., Landis, D.M.D., Brightman, M.W., 1975. Junctions in the meninges and marginal glia. J. Comp. Neurol. 164, 127–169. Vladić, A., Klarica, M., Bulat, M., 2009. Dynamics of distribution of 3H-inulin between the cerebrospinal fluid compartments. Brain Res. 1248, 127–135. References

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