Patterns of Single-Gene Inheritance

1. Patterns of Single-Gene Inheritance

2. Patterns of Single-Gene Inheritance

3. Terminology and Concepts - Terminology

4. Terminology and Concepts � Kindred pedigree

5. Mendelian Inheritance

6. Mendelian Inheritance � Factors affecting inheritance

10. Mendelian Inheritance � Heterogeneity

11. Allelic heterogeneity � Cystic Fibrosis (autosomal recessive disorder)

12. Locus Heterogeneity � Retinis pigmentosa

13. Phenotypic Heterogeneity � Multiple Endocrine Neoplasia (MEN2) and Hirschsprung disease

14. Autosomal Pattern of Mendelian Inheritance Recessive and Dominant Patterns

15. Autosomal Recessive Inheritance

16. Autosomal Recessive Inheritance � Factors influencing the inheritance

17. Autosomal Recessive Inheritance - Consanguinity

18. Autosomal Recessive Inheritance � Consanguinity and Xeroderma pigmentosum

19. Autosomal Dominant Inheritance

20. Autosomal Dominant Inheritance - Achondroplasia

22. Sex-Linked Pattern of Mendelian Inheritance X-linked and Y-linked, Dominant and Recessive

26. X-Linked Disorders � RecessiveHemophilia or the �Royal Disease�

27. X-Linked Disorders � Recessive � Color Blindness

28. X-Linked Disorders � Dominant