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This study examines the impact of different OLZ dosage levels on the activity levels of mice using a wheel measuring system. Results show varying effects on plasma levels, with implications for dosing recommendations.
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120 100 80 08 mg/kg/day, No Wheel 08 mg/kg/day, Wheel OLZ Plasma Level (ng/mL) 60 16 mg/kg/day, No Wheel 16 mg/kg/day, Wheel 40 20 0