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Introduction Into Biochemistry

Biochemistry is the chemistry of life, unraveling the molecular mysteries of living organisms. Explore how biochemistry influences medicine, agriculture, industry, and the environment. Learn about the vital areas of biochemistry, including metabolism, molecular genetics, and the origins of this scientific field. Discover the principles and organization of life at the molecular level, from elements to cells to organisms. Delve into the fascinating world of biomolecules, polymers, and the intricate processes of condensation and hydrolysis.

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Introduction Into Biochemistry

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  1. Introduction IntoBiochemistry

  2. What is Biochemistry? • Biochemistry = chemistry of life. • Biochemists use physical and chemical principles to explain biology at the molecular level. • Basic principles of biochemistry are common to all living organism

  3. How does biochemistry impact you? • Medicine • Agriculture • Industrial applications • Environmental applications

  4. Principle Areas of Biochemistry • Structure and function of biological macromolecules • Metabolism – anabolic and catabolic processes. • Molecular Genetics – How life is replicated. Regulation of protein synthesis

  5. Origins of Biochemistry: A challenge to “Vitalism.” Famous Dead Biochemist!

  6. 1828 Friedrich Wohler Fallacy #1: Biochemicals can only be produced by living organisms • Dead Biochemist #1

  7. Fallacy #2: Complex bioconversion of chemical substances require living matter Dead Biochemists #2 • 1897 Eduard Buchner Glucose + Dead Yeast = Alcohol

  8. Fallacy #2: Complex bioconversion of chemical substances require living matter • Emil Fischer Dead Biochemists #3

  9. Organization of Life • elements • simple organic compounds (monomers) • macromolecules (polymers) • supramolecular structures • organelles • cells • tissues • organisms

  10. Range of the sizes of objects studies by Biochemist and Biologist 1 angstrom = 0.1 nm

  11. Important compounds, functional groups

  12. Many Important Biomolecules are Polymers lipids proteins carbo nucleic acids monomer polymer supramolecular structure

  13. monomer polymer supramolecular structure Lipids

  14. monomer amino acid polymer protein subunit supramolecular structure Enzyme complex Proteins

  15. Carbohydrates monomer polymer supramolecular structure

  16. Nucleic Acids monomer polymer supramolecular structure

  17. Common theme: Monomers form polymers through condensations Polymers are broken down through hydrolysis.

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