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Cristina Caterina Aldea Scientific Coordinator: Professor Ioan Ş tefan Florian MD, PhD “Iuliu Ha ţieganu ” University of Medicine and Pharmacy Cluj-Napoca. Vascular malformations. General considerations. Non-neoplastic Vascular Malformations of the Brain. Arteriovenous Malformations (AVMs)
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Cristina Caterina Aldea Scientific Coordinator: Professor Ioan Ştefan Florian MD, PhD “Iuliu Haţieganu”University of Medicine and Pharmacy Cluj-Napoca Vascular malformations. General considerations
Non-neoplastic Vascular Malformations of the Brain • Arteriovenous Malformations (AVMs) • Venous Angioma • Cavernoma • Capillary Teleangiectasia • Direct Fistula ( McCormick-1966 )
Clinical presentation 1. Hemorrhage - most common - 82% significant IP component - SAH, IVH 2. Seizures 3. Mass effect (increased ICP ) 4. Progressive Neurologic Deficit 7% of patients with AVMs present associated aneurysms
Imaging studies • CT scan • CT angiography • MRI / angio - MRI • Cerebral angiography
Cavernomas = cavernous angioma, cavernous hemangioma
Clinical presentation • Seizures • Progressive Neurological Deficit • Hemorrhage ( usually IP ) > 50 % asymptomatic
Imaging Studies • CT • MRI - hemosiderine ring( “salt and pepper” appearance ) • Angiography – “angiographically occult”