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Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system. classification. Anatomical Etiological :causes Pathological symptomology. Mononeuropathy mononeuropathy multiplex Generalized: polyneuropathy. Anatomical. etiological. acquired
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Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system.
classification • Anatomical • Etiological :causes • Pathological • symptomology
Mononeuropathy mononeuropathy multiplex Generalized: polyneuropathy Anatomical
etiological • acquired • VITAMIN D • V:vascuilities, SLE,PAN,.. • I:infection,HIV,CMV,EBV,leprosy • T: truma • A:autimmune • M:Metabolic:DM,vit B12 defciency,hypothyrodism,renal hepatic ,porphyria • I:Infiltrative:sarcidosis, amylodosis • N:Neoplasm: paraneoplastic • D:Demyelinating ,GBS(Guillian barre syndrome or Drugs • Hereditary ,
pathological • Axonal • demyelinating
onset • Acute chronic
Signs and symptoms • Motor :weakness+ lower motor neuron signs • Sensory: +ve or –ve symptoms, gloves and stalk distribution • Autonomic:incotenance, postural hypotention,
Work UP • EMG and nerve coduction study • Look for the causes • LP: protien, glu,WBC (cytoalbumin dissociation)..GBS • ANA,RF,vit B12,TFT,Glu leve,renal,… • Nerve biopsy
GBS • Acute inflamatory demyelinating poly radiculopathy • Preceded by URTI, diarrhea • Asending weaknesss • It is emergency • Diagnosed by EMG ,NCS and LP(cyto albumin dissociation)