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A. Training Profiles: Perturbation 1…N. B. C. D. Test Profiles. Survival. +Cor -Cor. Genes. SAM. Spearman Correlation significant?. Time. Survival analysis, EPSA score (correlation vs. pathway signature) as risk factor. Treated. Untreated.
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A. Training Profiles: Perturbation 1…N B. C. D. Test Profiles Survival +Cor -Cor Genes SAM Spearman Correlation significant? Time Survival analysis, EPSA score (correlation vs. pathway signature) as risk factor Treated Untreated Sort by EPSA score- degree of correlation with Pathway X Yes