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Does Cricoid Pressure Prevent Aspiration? Pro

Does Cricoid Pressure Prevent Aspiration? Pro. Rakesh B. Vadhera, MD, FRCA, FFARCSI Galveston, Texas. Introduction. “Linchpin” of Rapid Sequence Induction in Obstetrics Rozen 1981 1

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Does Cricoid Pressure Prevent Aspiration? Pro

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  1. Does Cricoid PressurePrevent Aspiration?Pro Rakesh B. Vadhera, MD, FRCA, FFARCSI Galveston, Texas

  2. Introduction • “Linchpin” of Rapid Sequence Induction in ObstetricsRozen1981 1 • Aspiration (with or without failed/difficult intubation): one of the main causes of anesthesia related morbidity & mortality 2,3

  3. Anesthesia-Related Deaths During Obstetric Delivery 1979-90 Hawkins 1997 4

  4. Introduction • Over 35 years: • It has become a standard of practice &a fail safe against aspiration • Since wide spread introduction of CP : • a decrease in the incidence of aspiration related mortality • CEMDGB-1988-90 3- no mortality

  5. How and Why?? • History dates back to 1770s, when CP was applied to stop gastric insufflation 5 • Monro 1770: in drowned people - a pressure that should not interrupt laryngeal patency • Hunter 1776 Caution: Pressure should be applied with “judgement” so that “Larynx and trachea remains patent”

  6. How and Why? • Most earlier research was done to prove that pressures below 40 mm Hg does not insufflate stomach: we have forgotten this part of research!!! • 1961: Sellick reintroduced CP, as a mean of preventing the regurgitation 6

  7. Why and Why Not?? • A simple mechanical and, physically, physiologically, and anatomically appropriate maneuver • Concern about it’s efficacy and safety • interfere with airway management • esophageal trauma/rupture • aspiration and • wrong application!!!!!!!!

  8. Physics • If lower as well as upper esophageal sphincters somehow become incompetent • Pressure in stomach is more than pharynx • How can you stop the flow (regurgitation)??? • You can not, except

  9. Physics • How can you stop the regurgitation? • Inside • Outside • Gravity

  10. How can you stop Regurgitation? • Reduce gastric pressure • Increase lower esophageal sphincter as well as barrier pressures • Increase upper esophageal sphincter pressure

  11. Physiology of Regurgitation • Full Stomach (volume and pH) • Increase in IGP • Reduction in LESP • Reduction in UESP • All these forces have to work together • BrP = LESP-IGP

  12. Gastro-esophageal Reflux • Normal physiological consequence of full stomach: reflux relaxation 7,8 • Esophageal pressure rises by 5-10 mm Hg 8 • equals gastric pressure • common cavity • Pathogenesis depends upon • mix factors • vary among individuals • difficult to identify

  13. Gastro-esophageal Reflux • Parturients: 8-13 • GER common • Low/incompetent LESP • 45-85%: h/o heart burns • 80% have GER and incompetent LES • Full stomach • Delayed gastric emptying

  14. IGP • Normally < 7 mm Hg 13 • 25 mm Hg in starved full term supine parturient 13 • Increased to 35 mm Hg when stomach is distended 7 • Additional insults • pressure • succinylcholine

  15. Lower Esophageal Sphincter • LESP is reduced:7-13 • spontaneously in GERD • in patients full stomach • in term parturients • h/o reflux and heart burns • with GA to 7-14 mm Hg, depending upon relaxation 14-16 • with CP: at CF of 20 N 15 17

  16. Upper Esophageal Sphincter • UESP is a “Second Line” defense • UESP normally 38 mm Hg :18is reduced < 10 mm Hg by • induction agents 19 • before loss of consciousness 19 • Laryngoscopy 20 • muscle relaxants 19

  17. Upper Esophageal Sphincter • Regurgitation occurs,if UESP < 25 mm Hg • UESP is restored by CP 18

  18. Application of CP

  19. Anatomy & Physiology of CP • Cricoid Cartilage (CC): • signet shaped ring • horizontal inferiorly • deep vertical lamina • CP • applied to anterior CC • obstructs the opening of esophagus • pushes CC against hypopharynx CPM E

  20. Anatomy & Physiology of CP • CF • Newton (9.81N=2.2lbs) • Esophagus • lower border of CC • opening guarded by • CC anteriorly • Cricopharyngeus muscle posteriorly • UES • 3 cm high pressure zone CPM E

  21. Application of CP Some VariationsHead & Neck PositionSingle Vs Double HandedTime of ApplicationHow much CF ?

  22. Head & Neck Position • Sellick : Tonsillectomy position 6,21 • anterior convexity of cervical spine • stretches esophagus • prevents lateral esophageal displacement • Magill’s position • better for intubation • must avoid flexion of the neck at atlanto-occipital joint 22

  23. Head & Neck Position • No difference in the efficacy of CP in patients WITH or WITHOUT pillow when CF > 15 N is applied.Vanner 1992 13 • Must avoid flexion of neck with CP 23 • Application from left side 24

  24. Time of Application • Apply CP, as Thiopentone is injectedSellick 1961 6 • Fear: application of CP in awake patients • pain • difficulty in breathing • trigger vomiting, retching & coughing

  25. Time of Application • Most discomfort occurs at a CF > 40 N • Most subjects tolerate CF of 20 N • Reduction in UESP commences before loss of consciousness “Must apply CP before loss of consciousness”Vanner 1992 13

  26. Single Vs Double Handed • SHCP • Thumb & middle finger on either side & index finger above • Prevents lateral movement Sellick 6 • Better option in routine circumstancesCook 25-27 Brimacombe 14

  27. Cricoid Force • CF should be such that it • prevents regurgitation • maintains laryngeal patency • Initial recommendations were to use CF of 44 N 28 • pain, retching and vomiting • fear of esophageal trauma • laryngeal patency

  28. Cricoid Force • Current recommendations:29 • 20 N before loss of consciousness • 20 N tolerated by most • Increase to 30 N with loss of consciousness 30 • UESP > IGP • prevents regurgitation, OP of 42 mm Hg • likely to maintain patency • least likely to cause trauma

  29. FEARS

  30. Fears • Airway Management • Aspiration • Esophageal Rupture • too much CP • badly applied CP • timing of CP • Wrong Application

  31. Airway Management • Biggest fear • anatomical distortion • difficult intubation / ventilation • Most of the data collected at > 44 N • Technique???

  32. Airway Management • Vanner 1997 31 • Better view • Backward & upward pressure • 6% chance of improvement by removing CP • Randell 1998 32 • Similar to BURP • 57/68 better view

  33. Airway Management • Learn from history • If you ever reach a scenario • Difficult to ventilate • Judgment says that you have a much better chance of intubation without CP

  34. Aspiration • Reported cases with the use of CP • Seen with • wrong application • CP taken off before securing the airwayHowell 1983 33 • Fault • procedure itself • wrong application • what if did not apply CP?????

  35. Esophageal Trauma/Rupture • Very few cases 34 • Unlikely because of direct pressure • pressure at level of hypopharynx • Only if high pressures develop during application • retching/vomiting

  36. Esophageal Trauma/Rupture • Minimized by • unconsciousness, muscle relaxation and CP to occur synchronously Sellick 1982 35 • no esophageal trauma reported in cadavers, if CF applied < 30 N Vanner 1992 30

  37. Wrong Application???

  38. Wrong Application • Does not mean it’s technique’s fault • Do something to learn the correct technique and teach others • Pediatric scale • Mannequin • Simulator training

  39. Consistent facts • LES/UES is reduced • gastric distension • pregnant women (heart burns/reflux) • anesthetic agents

  40. Consistent facts • CP • is the only “SECOND” line defense • restores UESP • should be applied before loss of consciousness

  41. Consistent facts • 30 N Cricoid Force is adequate • restore UESP • maintains laryngeal patency • Unlikely to cause esophageal trauma • We do not apply CP correctly • but can learn from training • need continuous training

  42. Non-consistent Facts • Airway management more difficult • too much CF • badly applied CP • SHCP may be a better option • Esophageal trauma • Aspiration with CP

  43. Recommendations • Feel for CC • CP must be applied to CC and not thyroid • CC in center (slightly right) • apply backward and upward pressure

  44. Recommendations • Maintain vertebral arch (sniffing position) • Apply correct force • pain on the bridge of the nose • 3-3.2 kg

  45. Case Senario • A pregnant women with h/o of heart burns, who drank wine and took some cocaine comes for a Stat C. section for abruption (and has DIC) • Diabetic, Gastroparesis, ate 2 hours ago, h/o regurgitation on lying flat, receiving heparin, comes for embolectomy

  46. Prevention Prevention Prevention

  47. Thanks

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