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Comprehensive Overview of the CITR Annual Report on Islet Transplant Procedures

This annual report presents a detailed summary of the Cellular Islet Transplant Registry (CITR), including recipient and donor characteristics, pancreas procurement, islet processing, and graft function data as of April 1, 2005. It covers insights from 19 islet transplant centers, detailing the number of infusion procedures and outcomes for recipients. The report also includes critical information about immunosuppressive medications and adverse events related to islet transplants, contributing to a better understanding of the effectiveness and challenges in islet transplantation.

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Comprehensive Overview of the CITR Annual Report on Islet Transplant Procedures

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  1. CITR Annual Report Exhibits CITR Annual ReportExhibitsPrepared by:CITR Coordinating CenterThe EMMES CorporationRockville, MDSponsored by:National Institute of Diabetes & Digestive & Kidney DiseasesNational Institutes of HealthBethesda, MDDatafile Closure: April 1, 2005

  2. Section 1: Registry Summary Section 2: Islet Transplant Alone Information Chapter 1: Recipient and Donor Characteristics Chapter 2: Pancreas Procurement and Islet Processing Chapter 3: Immunosuppressive and Other Medications Chapter 4: Graft Function Chapter 5: Recipient’s Laboratory Data Chapter 6: Adverse Events Section 3: Islet After Kidney Transplant Information CITR Coordinating Center CITR Committees Table of Contents

  3. Section 1: Registry Summary

  4. Contributing Islet Transplant Centers* (N=19)

  5. Summary of Information Representedin CITR Annual Reports

  6. Number of Islet Transplant Programs Transplanting and Number Reporting to CITR by Year

  7. Total Number of Infusion Procedures Conducted and Entered in CITR Database by Year and by Infusion Number (All Participants, N=138)

  8. Total Number of Infusion ProceduresReceived Per Recipient (All Participants, N=138)

  9. Summary of Transplant Types (All Participants, N=138)

  10. Summary of Information for Islet Transplant Alone Recipients

  11. Total Number of Islet Infusions Received forIslet Transplant Alone Recipients (N=118)

  12. Summary of Information for Islet After Kidney Recipients

  13. Total Number of Islet Infusions Received forIslet After Kidney Recipients (N=19)

  14. Section 2: Islet Transplant Alone Information

  15. Chapter 1: Recipient and Donor Characteristics

  16. Recipient Demographics

  17. Recipient Characteristics

  18. Recipient’s Primary Payer and Employment Status at Time of First Infusion

  19. Recipient Status at First Infusion

  20. Recipient Status at First Infusion(continued)

  21. Recipient Summary Measures at First Infusion

  22. Recipient Serology at Screening

  23. Infusion Summary by Infusion Sequence

  24. Donor Characteristics

  25. Donor Characteristics and HospitalizationSummary Information

  26. Donor Characteristics and HospitalizationSummary Information (continued)

  27. Donor Characteristics and HospitalizationSummary Information (continued)

  28. Donor Characteristics and HospitalizationSummary Information (continued)

  29. Donor Age (yrs)

  30. Donor Weight (kg)

  31. Donor Body Mass Index (kg/m2)

  32. Time from Cross Clamp toPancreas Recovery (mins)

  33. Donor Characteristics: Use of Vasopressors

  34. Donor Serology

  35. Donor Laboratory Data

  36. Donor Serum Creatinine (mg/dL)

  37. Donor BUN (mg/dL)

  38. Donor Total Bilirubin (mg/dL)

  39. Donor AST (IU/L)

  40. Donor ALT (IU/L)

  41. Donor Serum Lipase (IU/L)

  42. Donor Serum Amylase (IU/L)

  43. Donor Pre-Insulin Blood Glucose (mg/dL)

  44. Donor Maximum Blood Glucose (mg/dL)

  45. Chapter 2: Pancreas Procurement and Islet Processing

  46. Islet Processing Summary

  47. Islet Processing Summary (continued)

  48. Cold Ischemia Information

  49. Summary of Islet Equivalents and Timing of Count

  50. Islet Product Characterization

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