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This overview explores the complexities of genetic mutations, focusing on hemoglobin and its variants. It highlights normal hemoglobin versus mutated forms caused by point mutations, such as CTC to GAG, affecting genetic information. By understanding the roles of mutations—such as point and frame shift mutations—we can better comprehend genetic disorders and inheritance patterns. Keywords will be reviewed for upcoming classes, including mutation types, alleles, genotypes, and phenotypes, alongside discussions of genetic disorders and potential treatments.
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Normal hemoglobin Hemoglobin
Point Mutation CTC ACT CCT G AG GAG AAG TCT T Codon 1 Codon 2 Codon 3 Codon 1 Codon 4 Codon 2 Codon 5 Codon 3 Codon 6 Codon 4 Codon 7 Codon 5 Codon 6 Codon 7
Frame shift Mutation • AG GAG AAG TCT T CTC ACT CCT G Codon 1 Codon 2 Codon 3 Codon 1 Codon 4 Codon 2 Codon 5 Codon 3 Codon 6 Codon 4 Codon 7 Codon 5 Codon 6 Codon 7
Mutation • Change in DNA that affects genetic information
New vocab due next class(Put them on flashcards so you can study them!) Mutation, point mutation, frame shift mutation, Chromosome, Gene, Allele, Homologous, Homozygous, Heterozygous, Dominant allele, Recessive allele, Incomplete dominance, Codominance, Genotype, Phenotype
