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Essential Role of ERGIC in Membrane Recruitment of ATG14 and DFCP1

The study by Ge L. et al. published in eLife Sciences (2013) highlights the critical involvement of the ERGIC (Endoplasmic Reticulum-Golgi Intermediate Compartment) in the membrane recruitment of essential autophagy proteins, ATG14 and DFCP1. Disruption of ERGIC leads to inhibited recruitment, underscoring its significance in cellular autophagic processes. The findings provide insight into the mechanistic role of ERGIC in autophagy and its potential implications in various biological functions and diseases.

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Essential Role of ERGIC in Membrane Recruitment of ATG14 and DFCP1

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  1. ERGIC is required for membrane recruitment of ATG14 and DFCP1.(A) Disruption of ERGIC inhibits membrane recruitment of ATG14 and DFCP1. Ge L et al. eLife Sciences 2013;2:e00947

  2. ERGIC is required for membrane recruitment of ATG14 and DFCP1.(A) Disruption of ERGIC inhibits membrane recruitment of ATG14 and DFCP1. Ge L et al. eLife Sciences 2013;2:e00947

  3. ERGIC is required for membrane recruitment of ATG14 and DFCP1.(A) Disruption of ERGIC inhibits membrane recruitment of ATG14 and DFCP1. Ge L et al. eLife Sciences 2013;2:e00947

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