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This protocol outlines a treatment strategy for patients with Small Cell Lung Cancer (SCLC), specifically focusing on those classified as good responders. The regimen includes administering three cycles of CDDP (cisplatin), along with radiation therapy (XRT), at a dose of 45 Gy over 30 fractions (BID dosing), for patients with a performance status of 0-1. Additional treatment considerations include PCI (prophylactic cranial irradiation) for patients who respond favorably to initial therapy.
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R R Group A A A EP+CDDP N N EP+CDDP 3 cycles* LD - - D D 1 cycle SCLC O O XRT (BID) M M PS 0-1 45 Gy/30 fx I I Group B Z Z CPT CPT - - 11+CDDP 11+CDDP E E 3 cycles* 3 cycles* *PCI for good responders