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A Very Quick Update on Research in Amputees. Process. Search of AMED, Medline, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of SR, Cochrane Database of Abstracts of Reviews and Effects 22150 Entries 2010 87 entries. Process. Cochrane Reviews
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Process • Search of AMED, Medline, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of SR, Cochrane Database of Abstracts of Reviews and Effects • 22150 Entries • 2010 • 87 entries
Process • Cochrane Reviews • 4 (3 complete, 1 protocol)
Cochrane Reviews • At its core is the collection of Cochrane Reviews, a database of systematic reviews and meta-analyses which summarise and interpret the results of medical research. • The Cochrane Library aims to make the results of well-conducted controlled trials readily available and is a key resource in evidence-based medicine.
Pharmacological interventions for treating phantom limb pain (2009)
Phantom Pain • Do pharmacological agents given post operatively when phantom pain occurs provide : • Short term pain relief • Improved sleep • Changes in sleep • Changes in function • Changes in QOL
Transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain following amputation in adults (2010)
TENS for Phantom and Stump Pain • Criteria • All RCT’s • Adults with phantom limb or stump pain • TENS vs comparison group (ie no Rx, sham, a pharmacological intervention, a non-pharmacological intervention)
TENS for Phantom and Stump Pain • Outcome measures • Primary (Pain validated scale – VAS, NRS) • Secondary (lots)
TENS for Phantom and Stump Pain • 72 published studies initially identified • 14 considered relevant • Nil meet criteria
TENS for Phantom and Stump Pain • Insufficient evidence for practice • 10 of the 14 studies reported benefits from using TENS • 1 reported no benefit • 2 were inconclusive • 1 did not provide sufficient information
Prosthetic rehabilitation for older dysvascular people following a unilateral transfemoral review (2009)
Prosthetic Training • To summarise the evidence evaluating prosthetic rehabilitation interventions post TFA in older dysvascular patients • Criteria • RCT’s • Male or female over 60 years old • Living in the community or in institutional care • Dysvascular • A TFA or through knee amputation and provided a prosthesis for mobilising
Prosthetic Training • Interventions • Education on Don/doff • Education on skin care • Therapeutic interventions • Balance and mobility training • Functional training • General advice
Prosthetic Training • Primary measure • User satisfaction • Level of function • Amputee specific functional tests • Secondary measures • General quality of life measures
Prosthetic Training • 38 published studies initially identified • 5 considered relevant • 1 suitable for inclusion
Prosthetic Training • Prosthetic weight effect on gait speed and preference
Prescription of prosthetic ankle-foot mechanisms after lower limb amputation(2009)
Ankle-foot prescription • To establish precise criteria for the prescription of prosthetic ankle-foot mechanisms in individuals with lower limb amputations • Criteria • RCT’s and Quasi RCT’s • Comparing different types of feet
Ankle-foot mechanisms • Outcomes • Subjective findings • Energy expenditure • Stride characteristics • Kinetic and kinematic parameters
Ankle-foot Prescription • 348 references initially identified • 37 studies considered relevant • 26 suitable for inclusion
Ankle-foot Prescription • Insufficient evidence from high quality comparative studies for the overall superiority of any type of prosthetic foot ankle mechanism
Take Home message • A lack of high quality comparative studies • Lack of randomisation • Poor description of procedures