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A Very Quick Update on Research in Amputees

A Very Quick Update on Research in Amputees. Process. Search of AMED, Medline, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of SR, Cochrane Database of Abstracts of Reviews and Effects 22150 Entries 2010 87 entries. Process. Cochrane Reviews

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A Very Quick Update on Research in Amputees

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  1. A Very Quick Update on Research in Amputees

  2. Process • Search of AMED, Medline, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of SR, Cochrane Database of Abstracts of Reviews and Effects • 22150 Entries • 2010 • 87 entries

  3. Process • Cochrane Reviews • 4 (3 complete, 1 protocol)

  4. Cochrane Reviews • At its core is the collection of Cochrane Reviews, a database of systematic reviews and meta-analyses which summarise and interpret the results of medical research. • The Cochrane Library aims to make the results of well-conducted controlled trials readily available and is a key resource in evidence-based medicine.

  5. Pharmacological interventions for treating phantom limb pain (2009)

  6. Phantom Pain • Do pharmacological agents given post operatively when phantom pain occurs provide : • Short term pain relief • Improved sleep • Changes in sleep • Changes in function • Changes in QOL

  7. Transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain following amputation in adults (2010)

  8. TENS for Phantom and Stump Pain • Criteria • All RCT’s • Adults with phantom limb or stump pain • TENS vs comparison group (ie no Rx, sham, a pharmacological intervention, a non-pharmacological intervention)

  9. TENS for Phantom and Stump Pain • Outcome measures • Primary (Pain validated scale – VAS, NRS) • Secondary (lots)

  10. TENS for Phantom and Stump Pain • 72 published studies initially identified • 14 considered relevant • Nil meet criteria

  11. TENS for Phantom and Stump Pain • Insufficient evidence for practice • 10 of the 14 studies reported benefits from using TENS • 1 reported no benefit • 2 were inconclusive • 1 did not provide sufficient information

  12. Prosthetic rehabilitation for older dysvascular people following a unilateral transfemoral review (2009)

  13. Prosthetic Training • To summarise the evidence evaluating prosthetic rehabilitation interventions post TFA in older dysvascular patients • Criteria • RCT’s • Male or female over 60 years old • Living in the community or in institutional care • Dysvascular • A TFA or through knee amputation and provided a prosthesis for mobilising

  14. Prosthetic Training • Interventions • Education on Don/doff • Education on skin care • Therapeutic interventions • Balance and mobility training • Functional training • General advice

  15. Prosthetic Training • Primary measure • User satisfaction • Level of function • Amputee specific functional tests • Secondary measures • General quality of life measures

  16. Prosthetic Training • 38 published studies initially identified • 5 considered relevant • 1 suitable for inclusion

  17. Prosthetic Training • Prosthetic weight effect on gait speed and preference

  18. Prescription of prosthetic ankle-foot mechanisms after lower limb amputation(2009)

  19. Ankle-foot prescription • To establish precise criteria for the prescription of prosthetic ankle-foot mechanisms in individuals with lower limb amputations • Criteria • RCT’s and Quasi RCT’s • Comparing different types of feet

  20. Ankle-foot mechanisms • Outcomes • Subjective findings • Energy expenditure • Stride characteristics • Kinetic and kinematic parameters

  21. Ankle-foot Prescription • 348 references initially identified • 37 studies considered relevant • 26 suitable for inclusion

  22. Ankle-foot Prescription • Insufficient evidence from high quality comparative studies for the overall superiority of any type of prosthetic foot ankle mechanism

  23. Take Home message • A lack of high quality comparative studies • Lack of randomisation • Poor description of procedures

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