What Is New in HIV Infection? Journal of AAFP February 15, 2014 Volume 89, Number 4 Today is 3/26/14, and my name is Isaac Engholm, DO
Vignette: • 32 year old male • 240 lbs • 6’ 4” • Presents to clinic for his AHM. He is accompanied by his friend.
The next day… The Next Day….
What is PrEP? • PrEP is short for Pre-Exposure Prophylaxis
Truvada • Mechanism of Action Nucleoside and nucleotide reverse transcriptase inhibitor combination; emtricitabine is a cytosine analogue while tenofovirdisoproxilfumarate (TDF) is an analog of adenosine 5'-monophosphate. Each drug interferes with HIV viral RNA dependent DNA polymerase resulting in inhibition of viral replication.