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Peripheral Neuropathy

Peripheral Neuropathy. Peripheral Neuropathy. DEFINITION: It is inflammation and degeneration of the peripheral nerves and/or the cranial nerves resulting in impairment of the conductivity of these nerves. Classification of Neuropathy. 1- Mononeuropathy :

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Peripheral Neuropathy

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  1. Peripheral Neuropathy

  2. Peripheral Neuropathy DEFINITION: It is inflammation and degeneration of the peripheral nerves and/or the cranial nerves resulting in impairment of the conductivity of these nerves

  3. Classification of Neuropathy 1- Mononeuropathy: 2- Mononeuropathy multiplex: 3- Polyneuropathy:

  4. CAUSES OF MONONEUROPATHY: 1- Trauma: wrong injection into a nerve, callus compression. 2- Infective: leprosy, herpes zoster. 3- Vascular: polyarteritisnodosa. 4- Metabolic: diabetes mellilus.

  5. CAUSES OF POLYNEUROPATHY I-Heridofamilial: 1- Hypertrophic interstitial polyneuropathy. 2- Peroneal muscle atrophy. 3- Refsum's disease.

  6. Clinical Picture of polyneuropathy A- Motor:

  7. B- Sensory:

  8. Glove Hypothesia Stock

  9. C-Autonomic: Vasomotor:coldness and cyanosis of the limbs. Cutaneous:loss of hair, brittle nails, trophic ulcers.

  10. Specific Types of Polyneuropathy I- PERONEAL MUSCLE ATROPHY

  11. Peroneal muscle Atrophy Inverted Champagne-bottle appearance

  12. Diabetic Neuropathy Pathogenesis: Diabetic microangiopathy of the vasa nervosa. Ischaemia of the nerves, 2ry to atherosclerosis of the vasa nervosa.

  13. Treatment of Diabetic Neuropathy Proper management of diabetes: diet, oral hypoglycaemic drugs or insulin. VilaminsB1 100 mg daily, B6 200 mg daily, B12 1000 mg daily.

  14. Acute Infective PolyneuropathyLandary-Guillan-Barre Syndrome Aetiology: It is due to an allergic or auto-immune reaction secondary to a previous non-specific virus infection.

  15. Clinical Picture 1-Febrile stage: 2-Latent stage:

  16. 3-Paralytic stage: 

  17. PN Testing for diagnosis The EMG test itself: • Nerve Conduction Studies (NCS) • EMG (Needle portion)

  18. Treatment of GuillainBarre Syndrome

  19. Thank you

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