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a/b structures

Delve into the intricate world of enzyme structures with a focus on a/b barrels, leucine-rich motifs, and active sites. Learn about key enzymes such as Rubisco, triosephosphate isomerase, and tyrosyl-tRNA synthetase.

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a/b structures

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  1. a/b structures

  2. Triosephosphate dehydrogenase isomerase coenzyme-binding domain

  3. b-a-b motif in a right-handed structure

  4. a/b barrel

  5. a/b barrel

  6. An exception: Methylmalonyl-coenzyme A mutase

  7. Pyruvate kinase

  8. Synthesis of Tryptophan

  9. Phosphoribosyl Anthranilate (PRA) isomerase & indoleglycerol phosphate (IBP) synthase

  10. RuBisCo (ribulose bisphosphate carboxylase)

  11. Leucine-rich motif-a/b-horseshoe fold

  12. Consensus amino acid sequence & 2nd structure of the leucine-rich motifs

  13. Ribonuclease inhibitor

  14. Conserved leucine in the leucine-rich motif

  15. Open twisted a/b structures

  16. active site ～crevice

  17. active site ～crevice • The crevices occur when the strand order is reversed. • In topology diagram the connections from the carboxy ends of two adjacent b strands go in opposite directions, one to the left and one to the right.

  18. FMN-binding redox protein flavodoxin Adenylate kinase

  19. Hexokinase ATP-binding domain Phosphoglycerate mutase

  20. Tyrosyl-tRNA synthetase (a/b + a)

  21. Bound tyrosine to tyrosyl-tRNA synthetase

  22. Tyrosyl adenylate -- tyrosyl-tRNA synthetase

  23. Carboxypeptidase (mixed b sheet)

  24. Zinc environment in Carboxypeptidase

  25. Arabinose-binding protein

  26. Arabinose-binding protein-L arabinose

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