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Ethynylestradiol Effects on EROD and BFCOD Activity in Protein Metabolism

This study investigates the impact of ethynylestradiol at various concentrations (0.06 μM, 0.12 μM, and 1 μM) on the enzymatic activities of EROD and BFCOD expressed in pmol/mg protein/min. The data reveal dose-dependent variations in enzyme activities, with EROD activity decreasing at higher concentrations while BFCOD activity shows a significant shift, indicating potential metabolic interactions. These findings contribute to the understanding of ethynylestradiol's role in modulating liver metabolic pathways and implications for drug metabolism.

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Ethynylestradiol Effects on EROD and BFCOD Activity in Protein Metabolism

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  1. A 0.16 0.08 1/EROD activity (pmol/mg protein/min)-1 -40 -20 20 40 60 B Ethynylestradiol (M) 0.12 0.06 1/BFCOD activity (pmol/mg protein/min)-1 -150 -100 -50 50 100 150 Ethynylestradiol (M)

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