Eocene Systems Integrating Technology to Promote a Healthier Lifestyle

1. Eocene SystemsIntegrating Technology to Promote a Healthier Lifestyle Marcel B. Twahirwa, MD Diplomate of the American Board of Diabetes, Endocrinology & Metabolism Medical Advisor Edinburg, TX Dr. Twahirwa, what are your credentials? AACE? etcDr. Twahirwa, what are your credentials? AACE? etc

2. Diabetes Today: An Epidemic 24 million Americans now have diabetes 1.5 million new cases in 2005 more than 3500 each day Complications of diabetes are a major cause of mortality and morbidity (2002 statistics) >224,000 deaths 82,000 amputations >44,000 began treatment for kidney failure 12,000-24,000 become blind Cost in 2007: $174 billion total Over $42 billion increase since 2002 90% of patients with diabetes are treated by Primary Care Physicians Extremly Brief! Highlight 24 million Americans with diabetes in 2007 Cost $174 billion healthcare dollars in 2007, increased $42 billion in just 5 years 90% of pts treated by PCPs, need more focus, Endo support and better tools Extremly Brief! Highlight 24 million Americans with diabetes in 2007 Cost $174 billion healthcare dollars in 2007, increased $42 billion in just 5 years 90% of pts treated by PCPs, need more focus, Endo support and better tools

3. Current State Of Glucose Monitoring�Up Against All Odds� Patient Compliance & Commitment is Diminishing Integrity, Even Existence of Logbook Increasing Time between office visits evaluation of current regimen review & modify medical therapy physician focused on patient High-Risk Diabetic Populations are Increasing Gestational Pediatric (Type 1 & Type 2) Geriatric Hispanic Native American African American Glycemic Targets & Treatment Goals More Aggressive initiate insulin therapy, titrate current insulin regimen, add or intensive insulin regimeninitiate insulin therapy, titrate current insulin regimen, add or intensive insulin regimen

4. ACE/AACE Position Statement Outpatient DM Management � 2005

5. Evolution of Diabetes Care

6. Evolution in Glucose Management: Introducing the Eocene System Comprehensive Diabetes Management & Compliance System enhances quality of care & data sharing THREE Simple Elements to system: Patients capture BG readings in Eclipse Monitor, just like any other traditional BG Meter Patient syncs Eclipse meter with home docking station where BG data is auto-synced to secure, central server Physician accesses web-based app on ANY Internet portal and patient�s BG data is presented real-time in full-color graphs Multiple options to display data & identify trends User-friendly interface & data presentation Option to set alarms & glucose boundaries

7. Eocene System: Creating a New Era of Patient Care Enhancing Glucose Management to Meet Patient Needs Eliminates diaries/logbooks, less patient responsibility, tasks Readings stored electronically, reduces errors & omissions Highly accurate BG Meter, small blood sample size Detailed Compliance & Outcome Reports Demonstrates how well patient is managing their diabetes Increases Compliance (Big Brother Principle) Refill Alerts to Patient and DME Supplier

8. Eocene System: Providing the Missing Link to Physicians Providing Physicians Valuable Insight into Patient�s Diabetes Care Time efficient resource, log-in whenever you need 24/7 Full-color, easy to interpret graphs and charts No forgotten logbooks or false information during office visits Improved glucose management and patient contact reduces cumbersome office check-ups & related travel Efficient communication between physician & patient that provides real-time info, ability to spot high or low BG Measure compliance by tallying physician-directed BG readings vs. actual BG readings completed Allows physician oversight & improves compliance Easy to teach and learn, like all glucometers, just dock it HIPAA Compliant System, Secure network

9. Eocene System: Connecting All Stakeholders Managed Care / Insurance Company Data Sharing Evaluate patient�s diabetes management & compliance, reward for good results Support physician billing & reimbursements Excellent document to support medical care in proposed �Pay for Performance� Initiatives Share with referring physicians to evaluate progress & disclose patient�s glucose management for records Serves as resource for family members to stay current with diabetes care, provide encouragement and support Communicate & review patient care from Home Health, PT & other healthcare team members Oversight Provides High-Quality Patient Care by ALL!! No Cost to the Physician, Patient or Payor!!

10. Summary slide, visual of entire process of system, multiple beneficiaries, checks & balances, data sharing, oversightSummary slide, visual of entire process of system, multiple beneficiaries, checks & balances, data sharing, oversight

11. Security & Infrastructure Dependable, secure data network & back-up system End-to-end encryption network: 128-bit SSL encryption Application Servers are housed in Tier 4 data center Eleven network providers; BGP4 technology 24/7 Back-up systems for all equipment 24/7 On-site security personnel & IT support All data is backed up hourly & stored off-site HIPAA Compliant, exceeds ALL requirements Background: http://en.wikipedia.org/wiki/Data_center A data center or datacenter (or datacentre), also called a server farm,[1] is a facility used to house computer systems and associated components, such as telecommunications and storage systems. It generally includes redundant or backup power supplies, redundant data communications connections, environmental controls (e.g., air conditioning, fire suppression) and security devices. The TIA-942:Data Center Standards Overview describes the requirements for the data center infrastructure. The simplest is a Tier 1 data center, which is basically a computer room, following basic guidelines for the installation of computer systems. The most stringent level is a Tier 4 data center, which is designed to host mission critical computer systems, with fully redundant subsystems and compartmentalized security zones controlled by biometric access controls methods. Another consideration is the placement of the data center in a subterranean context, for data security as well as environmental considerations such as cooling requirements. Is 128-bit SSL encryption really stronger than 40-bit SSL encryption?Absolutely. When an SSL handshake occurs between a client and server, a level of encryption is determined by the browser, the client computer operating system, and in certain situations the SSL Certificate. Low-level encryption, 40- or 56-bits, is acceptable for sites with low-value information. However, a hacker with the time, tools, and motivation can crack the code in a matter of minutes. High-level encryption, at 128-bits, can calculate 288 times as many combinations as 40-bit encryption. That�s over a trillion times a trillion times stronger. That same hacker with the same tools would require a trillion years to break into a session protected by an SGC-enabled certificate. http://articles.techrepublic.com.com/5100-10878_11-1034774.html What is BGP4?BGP4 is an extremely complex routing protocol used to provide routing information for very large networks, such as those found at an ISP or a multinational corporation such as AT&T. BGP4 does not provide detailed routing information based on individual subnets. Instead, BGP4 stores routing information in the form of network summarization.Summarizing routes is very important for an environment that can support literally thousands of networks. Additionally, BGP4 uses complex metrics that determine the best route to a destination network. Because of its complexity and scalability, BGP4 is best suited only for the largest of networks.How does BGP4 work?Unlike the majority of routing protocols, BGP4 is a connection-oriented protocol. When BGP4 is initiated on a router, it establishes a Transmission Control Protocol (TCP) connection with its neighboring router(s). Using this TCP connection, the router exchanges a complete copy of its routing table. Once the exchange of routing information is complete, BGP4 only sends out incremental updates, as changes occur in the network.Two types of routes are defined by BGP4. These routes are internal BGP4 routes and external BGP4 routes. Internal BGP4 routes are routes within a single autonomous system. For example, all of the routes available through an entire college campus may be considered an internal BGP4 route.An external BGP4 route is a route between two different autonomous systems. An example of an external BGP4 route could be a route between two college campuses.Background: http://en.wikipedia.org/wiki/Data_center A data center or datacenter (or datacentre), also called a server farm,[1] is a facility used to house computer systems and associated components, such as telecommunications and storage systems. It generally includes redundant or backup power supplies, redundant data communications connections, environmental controls (e.g., air conditioning, fire suppression) and security devices. The TIA-942:Data Center Standards Overview describes the requirements for the data center infrastructure. The simplest is a Tier 1 data center, which is basically a computer room, following basic guidelines for the installation of computer systems. The most stringent level is a Tier 4 data center, which is designed to host mission critical computer systems, with fully redundant subsystems and compartmentalized security zones controlled by biometric access controls methods. Another consideration is the placement of the data center in a subterranean context, for data security as well as environmental considerations such as cooling requirements. Is 128-bit SSL encryption really stronger than 40-bit SSL encryption?Absolutely. When an SSL handshake occurs between a client and server, a level of encryption is determined by the browser, the client computer operating system, and in certain situations the SSL Certificate. Low-level encryption, 40- or 56-bits, is acceptable for sites with low-value information. However, a hacker with the time, tools, and motivation can crack the code in a matter of minutes. High-level encryption, at 128-bits, can calculate 288 times as many combinations as 40-bit encryption. That�s over a trillion times a trillion times stronger. That same hacker with the same tools would require a trillion years to break into a session protected by an SGC-enabled certificate. http://articles.techrepublic.com.com/5100-10878_11-1034774.html What is BGP4?BGP4 is an extremely complex routing protocol used to provide routing information for very large networks, such as those found at an ISP or a multinational corporation such as AT&T. BGP4 does not provide detailed routing information based on individual subnets. Instead, BGP4 stores routing information in the form of network summarization.

12. Infopia USA: Passion for Innovation Designing and manufacturing quality diagnostic devices for over a decade Advanced technology in diabetes-related products as a means of increasing individuals standard and quality of life Introduced the first manufacturer sponsored home patient monitoring system �Eocene System� assisting in the management of chronic conditions

13. Infopia Focus: Next Generation Eocene System Pursue Opportunity to establish Strategic Alliance/Partnership with Leading Diabetes Company Active Participant & Supporter of Diabetes, Medical and Trade Shows and Forums to introduce product and spread awareness Communication & Marketing Focus to further brand recognition and industry support Major Focus on R&D Innovation of current products (Wireless technology) Provide all-inclusive solution to share patient vitals

14. �Before the Eocene System, I never knew how my patients were doing until they would call me or come in for their appointments every 2-3 months. I used to have a policy in my office that simply states: �No logbook, No appointment.� I cannot treat a diabetic patient without accurate readings. Now my patients feel very comfortable because they know that I am there, receiving their glucose values instantaneously and I can intervene effectively, they know that I am very much involved in their battle with diabetes.� -- Marcel B. Twahirwa, M.D.

15. Questions & Discussion Background: http://en.wikipedia.org/wiki/Data_center A data center or datacenter (or datacentre), also called a server farm,[1] is a facility used to house computer systems and associated components, such as telecommunications and storage systems. It generally includes redundant or backup power supplies, redundant data communications connections, environmental controls (e.g., air conditioning, fire suppression) and security devices. The TIA-942:Data Center Standards Overview describes the requirements for the data center infrastructure. The simplest is a Tier 1 data center, which is basically a computer room, following basic guidelines for the installation of computer systems. The most stringent level is a Tier 4 data center, which is designed to host mission critical computer systems, with fully redundant subsystems and compartmentalized security zones controlled by biometric access controls methods. Another consideration is the placement of the data center in a subterranean context, for data security as well as environmental considerations such as cooling requirements. Is 128-bit SSL encryption really stronger than 40-bit SSL encryption?Absolutely. When an SSL handshake occurs between a client and server, a level of encryption is determined by the browser, the client computer operating system, and in certain situations the SSL Certificate. Low-level encryption, 40- or 56-bits, is acceptable for sites with low-value information. However, a hacker with the time, tools, and motivation can crack the code in a matter of minutes. High-level encryption, at 128-bits, can calculate 288 times as many combinations as 40-bit encryption. That�s over a trillion times a trillion times stronger. That same hacker with the same tools would require a trillion years to break into a session protected by an SGC-enabled certificate. http://articles.techrepublic.com.com/5100-10878_11-1034774.html What is BGP4?BGP4 is an extremely complex routing protocol used to provide routing information for very large networks, such as those found at an ISP or a multinational corporation such as AT&T. BGP4 does not provide detailed routing information based on individual subnets. Instead, BGP4 stores routing information in the form of network summarization.Summarizing routes is very important for an environment that can support literally thousands of networks. Additionally, BGP4 uses complex metrics that determine the best route to a destination network. Because of its complexity and scalability, BGP4 is best suited only for the largest of networks.How does BGP4 work?Unlike the majority of routing protocols, BGP4 is a connection-oriented protocol. When BGP4 is initiated on a router, it establishes a Transmission Control Protocol (TCP) connection with its neighboring router(s). Using this TCP connection, the router exchanges a complete copy of its routing table. Once the exchange of routing information is complete, BGP4 only sends out incremental updates, as changes occur in the network.Two types of routes are defined by BGP4. These routes are internal BGP4 routes and external BGP4 routes. Internal BGP4 routes are routes within a single autonomous system. For example, all of the routes available through an entire college campus may be considered an internal BGP4 route.An external BGP4 route is a route between two different autonomous systems. An example of an external BGP4 route could be a route between two college campuses.Background: http://en.wikipedia.org/wiki/Data_center A data center or datacenter (or datacentre), also called a server farm,[1] is a facility used to house computer systems and associated components, such as telecommunications and storage systems. It generally includes redundant or backup power supplies, redundant data communications connections, environmental controls (e.g., air conditioning, fire suppression) and security devices. The TIA-942:Data Center Standards Overview describes the requirements for the data center infrastructure. The simplest is a Tier 1 data center, which is basically a computer room, following basic guidelines for the installation of computer systems. The most stringent level is a Tier 4 data center, which is designed to host mission critical computer systems, with fully redundant subsystems and compartmentalized security zones controlled by biometric access controls methods. Another consideration is the placement of the data center in a subterranean context, for data security as well as environmental considerations such as cooling requirements. Is 128-bit SSL encryption really stronger than 40-bit SSL encryption?Absolutely. When an SSL handshake occurs between a client and server, a level of encryption is determined by the browser, the client computer operating system, and in certain situations the SSL Certificate. Low-level encryption, 40- or 56-bits, is acceptable for sites with low-value information. However, a hacker with the time, tools, and motivation can crack the code in a matter of minutes. High-level encryption, at 128-bits, can calculate 288 times as many combinations as 40-bit encryption. That�s over a trillion times a trillion times stronger. That same hacker with the same tools would require a trillion years to break into a session protected by an SGC-enabled certificate. http://articles.techrepublic.com.com/5100-10878_11-1034774.html What is BGP4?BGP4 is an extremely complex routing protocol used to provide routing information for very large networks, such as those found at an ISP or a multinational corporation such as AT&T. BGP4 does not provide detailed routing information based on individual subnets. Instead, BGP4 stores routing information in the form of network summarization.