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Skin tumors

Skin tumors. Typical rodent ulcer. Basal cell carcinoma A malignant neoplasm of skin made up of cells from the basal layer of epidermis and adnexal structures.

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Skin tumors

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  1. Skin tumors

  2. Typical rodent ulcer Basal cell carcinoma A malignant neoplasm of skin made up of cells from the basal layer of epidermis and adnexal structures.

  3. Basal cell carcinoma: Typical growth pattern displaying as nest of basal cells with basal palisading. Melanin pigment is also seen ingested by the basal cells in the lesion.

  4. Seborrheic keratosisA benign neoplasm of keratinocytes on hair bearing areas that consists of pigmented macules, papules and plaques. There are several types and some are related to sun-exposure.

  5. Normal skin Seborrheic keratosis: -The lesion is composed of thick layer of basalloid cells with hyperpigmentation in most case. -Pseudohorn cysts are usually seen amid the lesion.

  6. SQUAMOUS CELL CARCINOMA A malignant neoplasm of keratinocytes that when present as a keratotic macule or papule on skin damaged badly by sunlight is referred to as solar keratosis (Actinic keratosis). When present as a plaque it is termed Bowen’s disease, and when present as many papules in the anogenital region it is called bowenoid papulosis. Solar keratosis, Bowen’s disease, and bowenoid papulosis, as well as arsenical keratosis and radiation keratosis, are euphemisms for various types of superficial squamous-cell carcinoma.

  7. Bowen’s Disease Solar (actinic) keratosis Arsenical keratosis

  8. Invasive squamous cell carcinoma Exophytic (cauliflower growth) and ulcerative lesions

  9. Normal skin

  10. Squamous cell carcinoma in situ

  11. Invasive Squamous Cell Carcinoma in situ Keratin pearl

  12. Melanocytic Nevus There are many names given to melanocytic nevi, both common and uncommon ones, e.g., Meisher, Unna, Spitz, Blue, Becker, Junctional , Compound, Intradermal , Deep penetrating, Halo, Dysplastic and more.

  13. Intradermal nevus: -Nevus cells (groups of melanocytes seen limited in the dermal layer

  14. “Dysplastic” Nevus Syndrome (Most patients are Caucasians)

  15. Malignant melanoma

  16. Early lesion is flat or slightly elevated

  17. Flat and nodular lesions

  18. Melanoma on palm or sole (Common in Asians)

  19. Nodular lesion of Melanoma

  20. Melanoma with ulcerated pigmented lesion

  21. Prognosis of melanoma depends on tumor thickness. The 5-year disease free survival is 98% for a lesion less than 0.75 mm thick and about 50% for a lesion over 1.5 mm.

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