1. 7th ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based Guidelines

2. Grade 1 Recommendations RCT = randomized controlled trial

3. Grade 2 Recommendations RCT = randomized controlled trial

4. Treatment of Venous Thromboembolic Disease

5. Initial Therapy for Acute DVT of the Leg • We recommend that patients receive anticoagulants as soon as the diagnosis of DVT is confirmed • Interim treatment should be started if suspicion is high and confirmation is delayed

6. Guidelines for Initial Treatment

7. Initial UFH or LMWH Therapy

8. Initial UFH or LMWH Therapy, continued

9. Systemic Thrombolysis as Initial Therapy

10. Systemic Thrombolysis as Initial Therapy, continued

11. Long-term Therapy for DVT of the Leg

12. Long-term Therapy for DVT of the Leg, continued *Established LMWH regimens for long-term treatment: dalteparin, 200 IU/kg body weight qd for 1 month, then 150 IU/kg qd; or tinzaparin, 175 IU/kg body weight SC qd.

13. Long-term Therapy for DVT of the Leg, continued

14. Long-term Therapy for DVT of the Leg, continued

15. Initial Therapy for PE: LMWH Or UFH Therapy

16. Initial Therapy for PE: Thrombolytic Agents

17. Initial Therapy for PE: Additional Recommendations

18. Initial Therapy for PE: Additional Recommendations, continued

19. Long-Term Therapy for PE: VKA Therapy

20. Long-Term Therapy for PE:VKA Therapy, continued

21. Long-Term Therapy for PE:VKA Therapy, continued

22. Postthrombotic Syndrome

23. Other Thrombotic Conditions

24. Other Thrombotic Conditions, continued

25. Other Thrombotic Conditions, continued