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Etude de l axe de la croissance staturale

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Etude de l axe de la croissance staturale

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    1. Etude de laxe de la croissance staturale 1- Les facteurs Hypothalamiques (GHRH, Ghrline, SS-14) 2- Le facteur Anthypophysaire : la GH 3- Le facteur Hpatique : lIGF1 4- Rgulation de laxe de la croissance staturale (Rgulation de la libration de la GH) 5- Mcanisme molculaire daction de la GH 6- GH endocrine / paracrine / autocrine 7- Autres fonctions de la Somatostatine 14 (SS-14)

    2. Axe de la croissance staturale (10) Liaison GH GHR 1 molcule GH 2 sites de liaison avec 2 molcules GH-R Dimrisation Activation de GH-R

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