660 likes | 776 Vues
This document provides a comprehensive overview of various mass analyzers, including Magnetic Sector Instruments, Quadrupole Instruments (QUADS), Ion Trap (TRAPS), Time-of-Flight (TOF) spectrometers, and Fourier Transform Ion Cyclotron Resonance (FT-ICR) spectrometers. It explores the stability diagrams for commercial ion traps, various scanning modes such as Parent Scan and Neutral Loss Scan, and discusses the motion of charged particles in magnetic fields. It also touches on MALDI techniques and ICR-FT-MS phenomena, making it a critical resource for researchers in mass spectrometry.
E N D
Types of Spectrometers Magnetic Sector Instruments Quadrupole Instrum [QUADS] Ion Trap [TRAPS] Time-of -Flight Instr. [TOF`s] Fourier Transform Ion Cyclotron Resonance [FT-ICR`s]
Stability Diagram for Commercial Traps LTQ ION TRAP
Scan-Modi eines TSQs F1 F2 F3 F21 F22 F23 M+ M+ etc Prod.ionen Scan F1 F2 F3 F21 F22 F23 FX+ M+ Parent Scan M+ etc F1 F2 F3 F21 F22 F23 M+ (M- X)+ Neutral Loss Scan M+ etc M+ (M+ X)+ Neutral Gain Scan M+ + X (M+ X)+ Q 2 Stoßzelle Q 3 Q 1
Dynode Turbo Q3 Q2 Q1 Q0 Inside the TSQ Quantum API
Time-of-Flight Mass Spectrometry • There are actually two type of mass analyzers in use for MALDI: • Reflectron time-of-flight mass spectrometer • Linear time-of-flight mass spectrometer