Organ Transplants New Frontiers
Xenotransplants • Animal to human • Experimental • First tried in 1906—pig kidney to human; goat liver to human • Baboon heart into human baby in 1984 • Two baboon livers into humans in 1992 • Baboon bone marrow into human AIDS patient in 1996
The Next Step • Genetically altered pig livers • Bridge until human liver is available • Contained three human genes that will produce human proteins to counter rejection
Questions for Investigation • Why baboons and pigs? • Which is favored? Why? • Are there other animals being considered? • Which mammal is the best match genetically? • Can stem cells lead to growing complete human organs?