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Blood lab. Blood composition. Plasma – fluid, gives volume contains antibodies Platelets – helps in clotting of blood White blood cells – used in defense against foreign invaders Red blood cells – carry oxygen. Blood after it has been centrifuged. Blood Genetics.
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Blood composition • Plasma – fluid, gives volume contains antibodies • Platelets – helps in clotting of blood • White blood cells – used in defense against foreign invaders • Red blood cells – carry oxygen Blood after it has been centrifuged
Blood Genetics • In blood type genetics*, there are: ____________ genes OR alleles that Produce ____________ blood proteins that Result in ____________ blood types that Establish ____________ genotypes THREE TWO FOUR SIX *See wkst #4
TERMS TO KNOW • Protein- antigen (ag) or agglutinogens • Antibodies- agglutinin- fight against foreign particles • Coagulation: Blood clotting • Agglutination: Blood clumping • RBC = Red blood Cell
Blood Groups Are Based On RBC Antigens (Ag) ‘A’ Ag Rh+ Antigen
Blood Groups: B+ and B- ‘B’ Ag Rh+ Antigen
Blood Groups: AB+ and AB- ‘A’ Ag ‘B’ Ag Rh+ Antigen
Blood Groups: O+ and O- Rh+ Antigen
Plasma Has Antibodies http://www.lrc.arizona.edu/courses/mmiweb/lake/immunology_modules/hemagglutination/hema2.html
YES NO NO NO YES YES NO
RECIPIENT DONOR + - - + - + + - - + + + - - - -
Rh Factor RR, Rr rr yes no anti Rh no Moms that have Rh negative blood will have antibodies/ fight against a baby with the Rh protein (positive).
1st Baby Is Rh + ; Mom is Rh - Baby’s blood enters mom’s blood, transferring Rh+ Antigens to mom
1st Baby Is Rh +; Mom Is Rh - Mom Makes Antibodies against Rh+ Antigens In Her Blood
2nd Baby Is Also Rh + Mom’s Antibodies Attack The RBC’s In The 2nd Baby
1st Baby Is Rh + Rhogam prevents Mom From Making Antibodies against Rh+ Antigens
2nd Baby Is Also Rh + With Rhogam, Mom’s Blood Does Not Attack The RBC’s In The 2nd Baby
Jaundice in Infants • Complications Due to ABO Incompatibility Are Rare!
RXN NORXN TYPE O TYPE A TYPE B TYPE AB http://waynesword.palomar.edu/aniblood.htm