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Pellagra is a nutritional deficiency disorder caused by a lack of niacin (Vitamin B3), often linked to diets heavily reliant on corn. Symptoms include atrophic glossitis, characterized by a smooth tongue due to loss of papillae, and gingivitis, often caused by poor oral hygiene but sometimes associated with pellagra. The condition can also affect fertility. Goldberger demonstrated in 1926 that a balanced diet or small amounts of baker's yeast could prevent pellagra. Key food sources of niacin include meat, fish, dairy, and fresh vegetables.
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Atrophic glossitisThe tongue appears smooth because of loss of filiform or fungiform papillae. Atrophic glossditis can be seen in pellagra & perinicous anemia
GingivitisPoor oral hygiene is the main cause .However , it can occur to other causes e.g. pellagra
List of drugs causing pellagroid dermatitisGarg , G & Khopkar, U IJVDL 77: 634, 2O112
Pellagra is caused by deficiency of niacine (B3)It occurs in people who are eating corn as a stable food .Goldberger established in 1926 that a balanced diet or small amount of baker’s yeast prevented pellagra.. Later , it was established that niacine (B3) cure pellagra in humans .The important source of niacine in our food are: meat, poultry, fish, milk, egg, dairy products, yeast, sunflower seeds, fresh vegetables..
