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Power Calculation for QTL Association

Power Calculation for QTL Association. Pak Sham, Shaun Purcell Twin Workshop 2001. Biometrical model. Genotype AA Aa aa Frequency (1-p) 2 2p(1-p) p 2 Trait mean -a d a Trait variance ? 2 ? 2 ? 2 Overall mean a(2p-1)+2dp(1-p). P ( X ) = ? G P ( X | G ) P ( G ).

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Power Calculation for QTL Association