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Biometrical Genetics

Biometrical Genetics

Biometrical Genetics. Shaun Purcell Twin Workshop, March 2004. Single locus model. Genetic effects ? variance components Genetic effects ? familial covariances Variance components ? familial covariances. A DE Model for twin data. [0.25/1]. [0.5/1]. 1. 1. 1. 1. 1. 1. E. D. A.

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663 views • 65 slides
Biometrical Genetics

Biometrical Genetics

Biometrical Genetics. Shaun Purcell Twin Workshop, March 2004. Single locus model. Genetic effects ? variance components Genetic effects ? familial covariances Variance components ? familial covariances. A DE Model for twin data. [0.25/1]. [0.5/1]. 1. 1. 1. 1. 1. 1. E. D. A.

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694 views • 65 slides
Biometrical genetics

Biometrical genetics

Biometrical genetics. Manuel AR Ferreira. Massachusetts General Hospital. Harvard Medical School. Boston. Boulder, 2008. Revisit common genetic parameters - such as allele frequencies, genetic effects, dominance, variance components, etc.

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1.14k views • 58 slides
Biometrical genetics

Biometrical genetics

Biometrical genetics. Pak C Sham The University of Hong Kong Manuel AR Ferreira Queensland Institute for Medical Research. 23 rd International Workshop on Methodology of Twin and Family Studies 2 nd March, 2010. A DE Model for twin data. 1 / 0.25. MZ / DZ. 1 / 0.5. E 1. D 1. A 1.

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558 views • 53 slides
Practical

Practical

Practical. H:ferreirabiometricsgene.exe. Practical. Aim. Visualize graphically how allele frequencies, genetic effects, dominance, etc, influence trait mean and variance. Ex1. a=0, d=0, p=0.4, Residual Variance = 0.04, Scale = 2. Vary a from 0 to 1. Ex2.

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321 views • 16 slides

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