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Cell death in PD: the case for mitochondria

Cell death in PD: the case for mitochondria

Cell death in PD: the case for mitochondria. Background. defects in the capacity of the ubiquitin-proteasome system (UPS) to degrade unwanted proteins is considered to play a role in the pathogenesis of PD

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241 views • 24 slides
Bcl-2: A Matter of Life-or-Death

Bcl-2: A Matter of Life-or-Death

Bcl-2: A Matter of Life-or-Death. Sarah Greenblatt Biology 169. Overview:. Importance of Apoptosis Apoptosis pathway: C. elegans What is the normal biological role of Bcl-2? How does Bcl-2 contribute to cancer?. Importance of Apoptosis. Embryonic and fetal development

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406 views • 20 slides
Bcl-2: A Matter of Life-or-Death

Bcl-2: A Matter of Life-or-Death

Bcl-2: A Matter of Life-or-Death. Sarah Greenblatt Biology 169. Overview:. Importance of Apoptosis Apoptosis pathway: C. elegans What is the normal biological role of Bcl-2? How does Bcl-2 contribute to cancer?. Importance of Apoptosis. Embryonic and fetal development

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351 views • 20 slides
Id proteins as determinants of drug sensitivity in B chronic lymphocytic leukaemia

Id proteins as determinants of drug sensitivity in B chronic lymphocytic leukaemia

Id proteins as determinants of drug sensitivity in B chronic lymphocytic leukaemia Sarah Weiler 1 , Debo Ademokun 2 , Andrew Poynter 3 and John Norton 1 1 Department of Biological Sciences, University of Essex, 2 Departments of Haematology and 3 Radiotherapy, Ipswich Hospital NHS Trust.

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334 views • 19 slides
Supplementary Fig. 1

Supplementary Fig. 1

A. Bcl-xL -/-. Bcl-xL +/+. B. Mcl-1 -/-. Mcl-1 +/+. Supplementary Fig. 1. A. Bcl-xL -/- No.1 T1. Bcl-xL -/- No.3 T1. Bcl-xL +/+. Bcl-xL -/- No.1NT. Bcl-xL -/- No.1 T2. Bcl-xL -/- No.2 NT. Bcl-xL -/- No.2 T1. Bcl-xL -/- No.2 T2. Bcl-xL -/- No.2 T3. Bcl-xL -/- No.3 NT.

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108 views • 5 slides
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87 views • 2 slides
0 5 10 0 5 10

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Supplementary Fig. GST. Addition. rANX II. Cisplatin ( m M ). 0 5 10 0 5 10. Bcl-xL. Bax. Actin. GST. 2.5. rANX II. 2.0. 1.5. Relatieve amount (Bcl-xL/Bax). 1.0. 0.5. 0. 0. 10. 5. Cisplatin ( m M).

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104 views • 1 slides

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