'Binding affinity' diaporamas de présentation

Genome evolution:

Genome evolution:. Lecture 11: Transcription factor binding sites. Sequence specific transcription factors. Sequence specific transcription factors (TFs) are a critical part of any gene activation or gene repression machinary

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Globins

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? ? ? ? ? ?. ? ? ? ? ? ? ? ? ? ? ? ? ? ?. Principles of anti-infective therapy. 1. Choice of proper anti-microbial agent 2. Anti-microbial combinations 3. Dosage and evaluation of efficacy. Choice of proper anti-microbial agent. Identification of infecting organism

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Biochemistry 412 2004 5 March Lecture Protein-Protein Interactions I

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Shuxing Zhang, Alexander Golbraikh and Alex Tropsha The Laboratory for Molecular Modeling

Development of Novel Geometrical Chemical Descriptors and Their Application to the Prediction of Ligand-Protein Binding Affinity. Shuxing Zhang, Alexander Golbraikh and Alex Tropsha The Laboratory for Molecular Modeling School of Pharmacy University of North Carolina at Chapel Hill

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Ongoing and Future Projects

Ongoing and Future Projects. Tianyin Zhou 4/9/2011. 1.FIS. Two binding sites: the binding affinity(left) 1000x stronger the binding affinity(right) Why? Left: The intrinsic shape of free DNA == Bound DNA ? more easily binding

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Using Molecular Biology to Develop a Novel Drug Targeting Antibiotic-Tolerant Lyme Persisters

Jonathan Locke BIOL-546. Using Molecular Biology to Develop a Novel Drug Targeting Antibiotic-Tolerant Lyme Persisters. Ixodes scapularis (deer tick) Eastern North America Ixodes pacificus Pacific North America Ixodes ricinus Europe. Ticks. 1. Anaplasmosis Babesiosis Bartonellosis

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Cell Surface Targeting: An Update.

Cell Surface Targeting: An Update. 7/10/2006. Outline. Streptavidin Fusion protein OmpA Other scaffolds Adaptamers. Lpp-OmpA surface display vehicle. Lipoprotein, Lpp: major outer membrane protein (most abundant protein in E. coli by numbers); targeted to outer membrane

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L Banci et al. Nature 000 , 1-4 (2010) doi:10.1038/nature09018

Determination of the relative Cu(I)-binding affinity of GSH and DETC. L Banci et al. Nature 000 , 1-4 (2010) doi:10.1038/nature09018.

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AJ Ehrlicher et al . Nature 000 , 1 - 4 (2011) doi:10.1038/nature10430

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AJ Ehrlicher et al . Nature 000 , 1 - 4 (2011) doi:10.1038/nature10430

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